Asahara T, Nakahara H, Fukuda T, Nakatani T, Yano M, Hino H, Okamoto Y, Katayama K, Itamoto T, Ono E, Dohi K, Kitamoto M, Nakanishi T
Department of Surgery II, Hiroshima University School of Medicine, Japan.
Hiroshima J Med Sci. 1998 Dec;47(4):151-5.
We evaluated the efficacy of percutaneous microwave coagulation therapy (PMCT) as compared with hepatectomy in 19 patients with hepatocellular carcinoma (HCC). In 6 patients with tumors more than 3 cm in diameter, coagulation was inadequate after a single session of PMCT. Patients with multiple tumors had recurrence within 1 year. For single tumors 3 cm or less in diameter, the therapeutic effectiveness of PMCT was comparable to that of hepatectomy in cumulative survival and cancer-free survival rates. We conclude that PMCT should be used in the initial treatment of HCC only in patients with single tumors of up to 3 cm in diameter. Surgical removal is recommended for tumors of more than 3 cm in diameter.
我们评估了19例肝细胞癌（HCC）患者经皮微波凝固治疗（PMCT）与肝切除术相比的疗效。在6例直径超过3 cm的肿瘤患者中，单次PMCT后凝固不充分。多发肿瘤患者在1年内复发。对于直径3 cm及以下的单发肿瘤，PMCT在累积生存率和无癌生存率方面的治疗效果与肝切除术相当。我们得出结论，PMCT仅应用于直径达3 cm的单发肿瘤患者的HCC初始治疗。对于直径超过3 cm的肿瘤，建议手术切除。
