Medsinge Anagha, Nischal Ken K
Pediatric Ophthalmology, Strabismus, and Adult Motility, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, (UPMC), Pittsburgh, PA, USA ; University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Clin Ophthalmol. 2015 Jan 7;9:77-90. doi: 10.2147/OPTH.S59009. eCollection 2015.
Cataract is a significant cause of visual disability in the pediatric population worldwide and can significantly impact the neurobiological development of a child. Early diagnosis and prompt surgical intervention is critical to prevent irreversible amblyopia. Thorough ocular evaluation, including the onset, duration, and morphology of a cataract, is essential to determine the timing for surgical intervention. Detailed assessment of the general health of the child, preferably in conjunction with a pediatrician, is helpful to rule out any associated systemic condition. Although pediatric cataracts have a diverse etiology, with the majority being idiopathic, genetic counseling and molecular testing should be undertaken with the help of a genetic counselor and/or geneticist in cases of hereditary cataracts. Advancement in surgical techniques and methods of optical rehabilitation has substantially improved the functional and anatomic outcomes of pediatric cataract surgeries in recent years. However, the phenomenon of refractive growth and the process of emmetropization have continued to puzzle pediatric ophthalmologists and highlight the need for future prospective studies. Posterior capsule opacification and secondary glaucoma are still the major postoperative complications necessitating long-term surveillance in children undergoing cataract surgery early in life. Successful management of pediatric cataracts depends on individualized care and experienced teamwork. We reviewed the etiology, preoperative evaluation including biometry, choice of intraocular lens, surgical techniques, and recent developments in the field of childhood cataract.
白内障是全球儿童视力残疾的一个重要原因,会对儿童的神经生物学发育产生重大影响。早期诊断和及时的手术干预对于预防不可逆的弱视至关重要。全面的眼部评估,包括白内障的发病、持续时间和形态,对于确定手术干预时机至关重要。详细评估儿童的整体健康状况,最好与儿科医生共同进行,有助于排除任何相关的全身性疾病。尽管儿童白内障病因多样,大多数为特发性,但对于遗传性白内障病例,应在遗传咨询师和/或遗传学家的帮助下进行遗传咨询和分子检测。近年来,手术技术和光学康复方法的进步显著改善了儿童白内障手术的功能和解剖学效果。然而,屈光性生长现象和正视化过程仍然困扰着小儿眼科医生,并凸显了未来进行前瞻性研究的必要性。后囊膜混浊和继发性青光眼仍是白内障手术患儿术后需要长期监测的主要并发症。成功管理儿童白内障取决于个性化护理和经验丰富的团队协作。我们回顾了儿童白内障的病因、术前评估(包括生物测量)、人工晶状体的选择、手术技术以及该领域的最新进展。