Mironova G D, Utesheva Zh A
Ukr Biokhim Zh (1978). 1989 Nov-Dec;61(6):48-54.
The molecular structure of the mitochondrial glycoprotein capable of forming Ca2+-selective and ruthenium red-sensitive conductance channels when incorporating into a model membrane are studied. The glycoprotein is shown to be a complex consisting of the glycoprotein itself and a low-molecular component which may be attributed to the substance of a peptide nature. A technique is elaborated to divide the complex into constituents. It is found that the channel-forming part of the complex is its peptide component. The glycoprotein component is unable to transport Ca2+ and, probably, fulfills a regulatory function.
研究了一种线粒体糖蛋白的分子结构,该糖蛋白在掺入模型膜时能够形成Ca2+选择性和钌红敏感的电导通道。结果表明,该糖蛋白是一种由糖蛋白本身和一种低分子成分组成的复合物,该低分子成分可能属于肽类物质。阐述了一种将该复合物分解为成分的技术。发现该复合物的通道形成部分是其肽成分。糖蛋白成分不能转运Ca2+,可能起调节作用。