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[粗制肝素及波兰产商业制剂的评估]

[Evaluation of crude heparin and commercial preparation of Polish production].

作者信息

Jarzebiński J, Tońska S, Remiszewska H

出版信息

Acta Pol Pharm. 1989;46(2):179-82.

PMID:2561044
Abstract

Contents of the solid residue, ash, nitrogen, hexosamines, uronic acids, carboxyl groups, and O- and N-sulphates, as well as mean molecular weights and anticoagulant activities of the crude heparin and the commercial product were compared. The study has confirmed the literature data concerning dependence of biological activity of heparin preparations upon their molecular weight.

摘要

比较了粗制肝素和市售产品的固体残渣、灰分、氮、己糖胺、糖醛酸、羧基以及O-和N-硫酸盐的含量,以及平均分子量和抗凝血活性。该研究证实了文献中关于肝素制剂的生物活性与其分子量相关性的数据。

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