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感染性气管憩室:一种与α-1抗胰蛋白酶缺乏症的罕见关联。

Infected tracheal diverticulum: a rare association with alpha-1 antitrypsin deficiency.

作者信息

Amaral Cecília Beatriz Alves, Silva Sónia, Feijó Salvato

机构信息

Hospital de Santa Maria, Northern Lisbon Hospital Center, Department of Internal Medicine, Lisbon, Portugal. Department of Internal Medicine, Northern Lisbon Hospital Center, Hospital de Santa Maria, Lisbon, Portugal.

Santarém Hospital, Santarém, Portugal. Santarém Hospital, Santarém, Portugal.

出版信息

J Bras Pneumol. 2014 Nov-Dec;40(6):669-72. doi: 10.1590/S1806-37132014000600011.

Abstract

Tracheal diverticulum, defined as a benign outpouching of the tracheal wall, is rarely diagnosed in clinical practice. It can be congenital or acquired in origin, and most cases are asymptomatic, typically being diagnosed postmortem. We report a case of a 69-year-old woman who was hospitalized after presenting with fever, fatigue, pleuritic chest pain, and a right neck mass complicated by dysphagia. Her medical history was significant: pulmonary emphysema (alpha-1 antitrypsin deficiency); bronchiectasis; and thyroidectomy. On physical examination, she presented diminished breath sounds and muffled heart sounds, with a systolic murmur. Laboratory tests revealed elevated inflammatory markers, a CT scan showed an air-filled, multilocular mass in the right tracheal wall, and magnetic resonance imaging confirmed the CT findings. Fiberoptic bronchoscopy failed to reveal any abnormalities. Nevertheless, the patient was diagnosed with tracheal diverticulum. The treatment approach was conservative, consisting mainly of antibiotics. After showing clinical improvement, the patient was discharged.

摘要

气管憩室被定义为气管壁的良性袋状膨出,在临床实践中很少被诊断出来。它可以是先天性的或后天获得性的,大多数病例无症状,通常在尸检时被诊断出来。我们报告一例69岁女性病例,该患者因发热、乏力、胸膜炎性胸痛以及伴有吞咽困难的右颈部肿块入院。她的病史较为复杂:患有肺气肿(α-1抗胰蛋白酶缺乏症)、支气管扩张症,并且接受过甲状腺切除术。体格检查发现她呼吸音减弱、心音低沉,伴有收缩期杂音。实验室检查显示炎症标志物升高,CT扫描显示右气管壁有一个充满气体的多房性肿块,磁共振成像证实了CT检查结果。纤维支气管镜检查未发现任何异常。尽管如此,该患者仍被诊断为气管憩室。治疗方法是保守治疗,主要使用抗生素。在病情出现临床改善后,患者出院。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bca/4301252/f61d15bd052b/1806-3713-jbpneu-40-06-00669-gf01.jpg

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