Kovács P, Csaba G, Török O
Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.
Acta Biol Hung. 1989;40(1-2):37-42.
Chinese hamster ovary (CHO) cells and Chang liver cells which had already interacted with a hormone (gonadotropin, TSH, insulin) in culture, transmitted hormonal imprinting to virgin cells not previously involved in the interaction. The information associated with imprinting was not mediated by the nutrient medium, because the nutrient medium of the hormone-treated cells did not induce imprinting in virgin cells and even reduced rather than enhanced the hormone binding capacity thereof. Thus the transmission of information is in all probability associated with a direct cell-cell contact.
在培养过程中已经与一种激素（促性腺激素、促甲状腺激素、胰岛素）相互作用的中国仓鼠卵巢（CHO）细胞和张氏肝细胞，将激素印记传递给了先前未参与该相互作用的未接触过该激素的细胞。与印记相关的信息不是由营养培养基介导的，因为经激素处理的细胞的营养培养基不会在未接触过该激素的细胞中诱导印记，甚至会降低而非增强其激素结合能力。因此，信息的传递很可能与细胞间的直接接触有关。
