极低出生体重儿新生儿早期的中心静脉压与肾功能
Central venous pressure and renal function in very low birth weight infants during the early neonatal period.
作者信息
Choi Yong-Sung, Lee Byong Sop, Chung Sung-Hoon, Kim Ji-Hee, Kim Ellen Ai-Rhan, Kim Ki-Soo
机构信息
a Department of Pediatrics , Kyung Hee University School of Medicine , Seoul , Korea .
b Department of Pediatrics , University of Ulsan College of Medicine, Asan Medical Center , Seoul , Korea , and.
出版信息
J Matern Fetal Neonatal Med. 2016;29(3):430-4. doi: 10.3109/14767058.2014.1002766. Epub 2015 Jan 23.
OBJECTIVE
To observe central venous pressure (CVP) and to address the association with hemodynamic and renal parameters in very low birth weight infants (VLBWI) during the early neonatal period.
METHODS
CVP levels were prospectively measured every 4 h in VLBWI with an umbilical venous catheter for at least the initial 5 d of life. The association of CVP with mean blood pressure, serum B-type natriuretic peptide, serum creatinine, fluid intake, and urine output were analyzed.
RESULTS
In 25 infants, the mean daily CVP (mCVP) value of 3.5 ± 2.2 mmHg did not change between day 1 and day 7 after birth. There were no significant correlations between mCVP and mean blood pressure, serum BNP, serum creatinine, fluid intake, and urine output over the total study period. However, the mCVP was significantly correlated with urine output and serum creatinine 96-144 h after birth.
CONCLUSIONS
After the transitional period, mCVP values were associated with renal function parameters in VLBWI.
目的
观察极低出生体重儿（VLBWI）在新生儿早期的中心静脉压（CVP），并探讨其与血流动力学及肾脏参数的关系。
方法
对VLBWI在出生后至少最初5天内，每4小时前瞻性地用脐静脉导管测量一次CVP水平。分析CVP与平均血压、血清B型利钠肽、血清肌酐、液体摄入量及尿量的关系。
结果
25例婴儿出生后第1天至第7天，平均每日CVP（mCVP）值为3.5±2.2 mmHg，无变化。在整个研究期间，mCVP与平均血压、血清BNP、血清肌酐、液体摄入量及尿量之间无显著相关性。然而，出生后96 - 144小时，mCVP与尿量及血清肌酐显著相关。
结论
过渡期后，VLBWI的mCVP值与肾功能参数相关。
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