Nordgaard Julie, Jürgens Gesche
Psykiatrisk Center Hvidovre, Brøndbyøstervej 160, 2605 Brøndby.
Ugeskr Laeger. 2015 Jan 26;177(2A):38-9.
A 38-year-old man was referred to the psychiatric department due to auditory hallucinations, suicidal ideation and a large daily intake of 8.4 g pregabalin. The Danish National Medication Register showed that the patient had bought pregabalin 21 times within the last two months, a total of 487.2 g pregabalin. Withdrawal symptoms disappeared within 48 hours, psychotic experiences and the suicidal ideations faded during the next couple of weeks. High doses of pregabalin are tolerated with surprisingly few toxicological consequences, though lethal cases have been described. Pregabalin abuse, however, can lead to dependency.
一名38岁男性因幻听、自杀意念以及每日大量服用8.4克普瑞巴林而被转诊至精神科。丹麦国家药物登记处显示，该患者在过去两个月内21次购买普瑞巴林，共计487.2克。戒断症状在48小时内消失，精神病性体验和自杀意念在接下来的几周内逐渐消退。尽管有致死病例的报道，但高剂量的普瑞巴林耐受性良好，毒理学后果出奇地少。然而，滥用普瑞巴林会导致成瘾。
