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距舟关节孤立性结核性骨髓炎,无肺部受累——1例罕见病例报告

Isolated tuberculous osteomyelitis of the talonavicular joint without pulmonary involvement-a rare case report.

作者信息

Chevannes Wystan, Memarzadeh Arman, Pasapula Chandra

机构信息

Orthopaedic Department, Queen Elizabeth Hospital, Kings Lynn PE30 4ET, UK.

Orthopaedic Department, Queen Elizabeth Hospital, Kings Lynn PE30 4ET, UK.

出版信息

Foot (Edinb). 2015 Mar;25(1):66-8. doi: 10.1016/j.foot.2014.11.005. Epub 2014 Dec 18.

Abstract

Tuberculosis is one of the leading causes of death worldwide amongst curable diseases. It is estimated that one-third of the world's population has been diagnosed with tuberculosis infection [1]. The prevalence is on the rise with an estimated 9.4 million new cases per year worldwide [1]. Tuberculosis most commonly presents with pulmonary involvement. However, approximately 23-30% of patients found to be infected with tuberculosis have extrapulmonary symptoms [2]. Of those, only 1-3% have been found to have osseous disease. Skeletal involvement with a primary focus of tuberculosis usually affects major weight-bearing joints such as the hip and knee. Tuberculosis infections of the foot and ankle are very rare, accounting for 1% of all tuberculosis infections [2-4]. Difficulties arise in the timing of diagnosis, patient compliance of therapy and awareness of the less obvious presenting symptoms. Musculoskeletal tuberculosis, although rare, can be a problem. Its uncommon site, non-specific presenting symptoms and its ability to mimic numerous disorders make it more difficult to formulate a definitive diagnosis and, in turn, leads to therapeutic delays [5-7]. It is for this reason that we report this case in an effort to promote awareness.

摘要

结核病是全球可治愈疾病中主要的死亡原因之一。据估计,全球三分之一的人口已被诊断出感染结核病[1]。其患病率呈上升趋势,全球每年估计有940万新病例[1]。结核病最常见的表现是肺部受累。然而,约23%-30%被发现感染结核病的患者有肺外症状[2]。其中,仅1%-3%被发现患有骨病。以结核为原发性病灶的骨骼受累通常影响主要负重关节,如髋和膝。足踝部的结核感染非常罕见,占所有结核感染的1%[2-4]。在诊断时机、患者治疗依从性以及对不太明显的症状表现的认识方面存在困难。肌肉骨骼结核虽然罕见,但可能是个问题。其发病部位不常见、症状表现不具特异性,且能够模仿多种病症,这使得明确诊断更加困难,进而导致治疗延误[5-7]。正是出于这个原因,我们报告此病例以提高认识。

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