Chevannes Wystan, Memarzadeh Arman, Pasapula Chandra
Orthopaedic Department, Queen Elizabeth Hospital, Kings Lynn PE30 4ET, UK.
Orthopaedic Department, Queen Elizabeth Hospital, Kings Lynn PE30 4ET, UK.
Foot (Edinb). 2015 Mar;25(1):66-8. doi: 10.1016/j.foot.2014.11.005. Epub 2014 Dec 18.
Tuberculosis is one of the leading causes of death worldwide amongst curable diseases. It is estimated that one-third of the world's population has been diagnosed with tuberculosis infection [1]. The prevalence is on the rise with an estimated 9.4 million new cases per year worldwide [1]. Tuberculosis most commonly presents with pulmonary involvement. However, approximately 23-30% of patients found to be infected with tuberculosis have extrapulmonary symptoms [2]. Of those, only 1-3% have been found to have osseous disease. Skeletal involvement with a primary focus of tuberculosis usually affects major weight-bearing joints such as the hip and knee. Tuberculosis infections of the foot and ankle are very rare, accounting for 1% of all tuberculosis infections [2-4]. Difficulties arise in the timing of diagnosis, patient compliance of therapy and awareness of the less obvious presenting symptoms. Musculoskeletal tuberculosis, although rare, can be a problem. Its uncommon site, non-specific presenting symptoms and its ability to mimic numerous disorders make it more difficult to formulate a definitive diagnosis and, in turn, leads to therapeutic delays [5-7]. It is for this reason that we report this case in an effort to promote awareness.
结核病是全球可治愈疾病中主要的死亡原因之一。据估计,全球三分之一的人口已被诊断出感染结核病[1]。其患病率呈上升趋势,全球每年估计有940万新病例[1]。结核病最常见的表现是肺部受累。然而,约23%-30%被发现感染结核病的患者有肺外症状[2]。其中,仅1%-3%被发现患有骨病。以结核为原发性病灶的骨骼受累通常影响主要负重关节,如髋和膝。足踝部的结核感染非常罕见,占所有结核感染的1%[2-4]。在诊断时机、患者治疗依从性以及对不太明显的症状表现的认识方面存在困难。肌肉骨骼结核虽然罕见,但可能是个问题。其发病部位不常见、症状表现不具特异性,且能够模仿多种病症,这使得明确诊断更加困难,进而导致治疗延误[5-7]。正是出于这个原因,我们报告此病例以提高认识。