Crabtree-Ramírez Brenda, Vega Yanink Neried Caro, Shepherd Bryan E, Turner Megan, Carriquiry Gabriela, Fink Valeria, Luz Paula M, Cortes Claudia P, Rouzier Vanessa, Padgett Denis, Jayathilake Karu, McGowan Catherine C, Person Anna K
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
AIDS Behav. 2015 Sep;19(9):1599-608. doi: 10.1007/s10461-014-0974-x.
In the United States (USA), the age of those newly diagnosed with HIV is changing, particularly among men who have sex with men (MSM). A retrospective analysis included HIV-infected adults from seven sites in the Caribbean, Central and South America network (CCASAnet) and the Vanderbilt Comprehensive Care Clinic (VCCC-Nashville, Tennessee, USA). We estimated the proportion of patients <25 years at HIV diagnosis by calendar year among the general population and MSM. 19,466 (CCASAnet) and 3,746 (VCCC) patients were included. The proportion <25 years at diagnosis in VCCC increased over time for both the general population and MSM (p < 0.001). Only in the Chilean site for the general population and the Brazilian site for MSM were similar trends seen. Subjects <25 years of age at diagnosis were less likely to be immunocompromised at enrollment at both the VCCC and CCASAnet. Recent trends in the USA of greater numbers of newly diagnosed young patients were not consistently observed in Latin America and the Caribbean. Prevention efforts tailored to young adults should be increased.
在美国，新诊断出感染艾滋病毒的人群年龄正在发生变化，尤其是在男男性行为者（MSM）当中。一项回顾性分析纳入了来自加勒比、中美洲和南美洲网络（CCASAnet）七个地点以及范德比尔特综合护理诊所（美国田纳西州纳什维尔的VCCC）的艾滋病毒感染成年人。我们按日历年估算了普通人群和男男性行为者中艾滋病毒诊断时年龄小于25岁的患者比例。共纳入了19466名（CCASAnet）和3746名（VCCC）患者。VCCC中普通人群和男男性行为者诊断时年龄小于25岁的比例均随时间增加（p<0.001）。仅在智利普通人群地点和巴西男男性行为者地点观察到类似趋势。在VCCC和CCASAnet，诊断时年龄小于25岁的受试者在入组时免疫功能低下的可能性较小。美国近期新诊断出的年轻患者数量增加的趋势在拉丁美洲和加勒比地区并未得到一致观察。应加大针对年轻人的预防力度。
