Matrix Gla protein limits pulmonary arteriovenous malformations in ALK1 deficiency.
作者信息
Boström Kristina I, Guihard Pierre, Blazquez Medela Ana M, Yao Jiayi, Moon Jeremiah H, Penton Ashley, Yao Yucheng
机构信息
Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA The Molecular Biology Institute at UCLA, Los Angeles, CA, USA
Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
出版信息
Eur Respir J. 2015 Mar;45(3):849-52. doi: 10.1183/09031936.00114714. Epub 2015 Jan 22.
Abstract
摘要
相似文献
1
Matrix Gla protein limits pulmonary arteriovenous malformations in ALK1 deficiency.基质γ-羧基谷氨酸蛋白可限制ALK1缺乏症中的肺动静脉畸形。
Eur Respir J. 2015 Mar;45(3):849-52. doi: 10.1183/09031936.00114714. Epub 2015 Jan 22.
2
Matrix Gla protein deficiency causes arteriovenous malformations in mice.基质 GLA 蛋白缺乏导致小鼠动静脉畸形。
J Clin Invest. 2011 Aug;121(8):2993-3004. doi: 10.1172/JCI57567. Epub 2011 Jul 18.
3
Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia.跨膜蛋白100（TMEM100）在血管完整性中起关键作用，但对遗传性出血性毛细血管扩张症的发病机制影响有限。
Cardiovasc Res. 2015 Mar 1;105(3):353-60. doi: 10.1093/cvr/cvu260. Epub 2014 Dec 23.
4
Activin-like kinase receptor 1 (ALK1) in atherosclerotic lesions and vascular mesenchymal cells.动脉粥样硬化病变和血管间充质细胞中的激活素样激酶受体1（ALK1）
Cardiovasc Res. 2007 May 1;74(2):279-89. doi: 10.1016/j.cardiores.2006.09.014. Epub 2006 Sep 27.
5
Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia.遗传性出血性毛细血管扩张症患者肺动脉高压的临床和分子遗传学特征
N Engl J Med. 2001 Aug 2;345(5):325-34. doi: 10.1056/NEJM200108023450503.
6
[Analysis of genetic mutation and modifier genes in pulmonary arterial hypertension].[肺动脉高压的基因突变及修饰基因分析]
Nihon Rinsho. 2008 Nov;66(11):2071-5.
7
De novo cerebrovascular malformation in the adult mouse after endothelial Alk1 deletion and angiogenic stimulation.成年小鼠内皮细胞 Alk1 缺失和血管生成刺激后新出现的脑血管畸形。
Stroke. 2014 Mar;45(3):900-2. doi: 10.1161/STROKEAHA.113.003655. Epub 2014 Jan 23.
8
Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling.动脉内皮特异性激活素受体样激酶1的表达表明其在动脉化和血管重塑中的作用。
Circ Res. 2003 Oct 3;93(7):682-9. doi: 10.1161/01.RES.0000095246.40391.3B. Epub 2003 Sep 11.
9
Clinical features of pulmonary arterial hypertension in young people with an ALK1 mutation and hereditary haemorrhagic telangiectasia.伴有ALK1突变和遗传性出血性毛细血管扩张症的年轻人肺动脉高压的临床特征
Arch Dis Child. 2009 Jul;94(7):506-11. doi: 10.1136/adc.2007.133082. Epub 2009 Apr 8.
10
[Screening for systemic manifestations of vascular malformations in patients with hereditary haemorrhagic telangiectasia (Osler disease)].[遗传性出血性毛细血管扩张症（奥斯勒病）患者血管畸形全身表现的筛查]
Acta Otorrinolaringol Esp. 2008 Nov;59(9):463-8.
引用本文的文献
1
Epigenetics enters the stage in vascular malformations.表观遗传学在血管畸形中登场。
J Clin Invest. 2024 Aug 1;134(15):e182904. doi: 10.1172/JCI182904.
2
Inhibition of endothelial histone deacetylase 2 shifts endothelial-mesenchymal transitions in cerebral arteriovenous malformation models.抑制内皮组蛋白去乙酰化酶2可改变脑动静脉畸形模型中的内皮-间充质转化。
J Clin Invest. 2024 May 23;134(15):e176758. doi: 10.1172/JCI176758.
3
Reply: Transitioning endothelial cells contribute to pulmonary fibrosis.回复：转化的内皮细胞有助于肺纤维化。
Eur Respir J. 2023 Sep 28;62(3). doi: 10.1183/13993003.01329-2023. Print 2023 Sep.
4
Regulating the cell shift of endothelial cell-like myofibroblasts in pulmonary fibrosis.调控肺纤维化中内皮细胞样肌成纤维细胞的细胞迁移。
Eur Respir J. 2023 Jun 8;61(6). doi: 10.1183/13993003.01799-2022. Print 2023 Jun.
5
Single-Cell RNA-Seq Identifies Dynamic Cardiac Transition Program from ADCs Induced by Leukemia Inhibitory Factor.单细胞 RNA-Seq 鉴定出由白血病抑制因子诱导的 ADC 中的心脏动态转变程序。
Stem Cells. 2022 Oct 21;40(10):932-948. doi: 10.1093/stmcls/sxac048.
6
Shaping Waves of Bone Morphogenetic Protein Inhibition During Vascular Growth.在血管生长过程中塑造骨形态发生蛋白抑制波。
Circ Res. 2020 Oct 23;127(10):1288-1305. doi: 10.1161/CIRCRESAHA.120.317439. Epub 2020 Aug 28.
7
The influence of a high fat diet on bone and soft tissue formation in Matrix Gla Protein knockout mice.高脂肪饮食对基质 Gla 蛋白敲除小鼠骨和软组织形成的影响。
Sci Rep. 2018 Feb 26;8(1):3635. doi: 10.1038/s41598-018-21650-0.
8
Matrix Gla protein regulates differentiation of endothelial cells derived from mouse embryonic stem cells.基质γ-羧基谷氨酸蛋白调节源自小鼠胚胎干细胞的内皮细胞分化。
Angiogenesis. 2016 Jan;19(1):1-7. doi: 10.1007/s10456-015-9484-3. Epub 2015 Sep 12.
本文引用的文献
1
Common and distinctive pathogenetic features of arteriovenous malformations in hereditary hemorrhagic telangiectasia 1 and hereditary hemorrhagic telangiectasia 2 animal models--brief report.遗传性出血性毛细血管扩张症1型和2型动物模型中动静脉畸形的共同和独特发病机制特征——简要报告
Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2232-6. doi: 10.1161/ATVBAHA.114.303984. Epub 2014 Jul 31.
2
Reducing Jagged 1 and 2 levels prevents cerebral arteriovenous malformations in matrix Gla protein deficiency.降低 Jagged1 和 Jagged2 水平可预防基质 Gla 蛋白缺乏症的脑动静脉畸形。
Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19071-6. doi: 10.1073/pnas.1310905110. Epub 2013 Nov 4.
3
Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium.无蹼蛋白 2 调控人及鼠血管内皮细胞中骨形态发生蛋白 9 的表达。
Blood. 2012 May 24;119(21):5037-47. doi: 10.1182/blood-2011-10-385906. Epub 2012 Apr 3.
4
Matrix Gla protein deficiency causes arteriovenous malformations in mice.基质 GLA 蛋白缺乏导致小鼠动静脉畸形。
J Clin Invest. 2011 Aug;121(8):2993-3004. doi: 10.1172/JCI57567. Epub 2011 Jul 18.
5
Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia.遗传性出血性毛细血管扩张症小鼠模型中新生动静脉畸形的实时成像
J Clin Invest. 2009 Nov;119(11):3487-96. doi: 10.1172/JCI39482. Epub 2009 Oct 1.
6
Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells.血管内皮生长因子的表达在内皮细胞中由激活素样激酶受体1和5协同调节。
Blood. 2009 Sep 3;114(10):2197-206. doi: 10.1182/blood-2009-01-199166. Epub 2009 Jun 8.
7
Hemodynamic forces, vascular oxidative stress, and regulation of BMP-2/4 expression.血流动力、血管氧化应激与 BMP-2/4 表达的调控。
Antioxid Redox Signal. 2009 Jul;11(7):1683-97. doi: 10.1089/ars.2008.2401.
8
Proline and gamma-carboxylated glutamate residues in matrix Gla protein are critical for binding of bone morphogenetic protein-4.基质Gla蛋白中的脯氨酸和γ-羧化谷氨酸残基对于骨形态发生蛋白-4的结合至关重要。
Circ Res. 2008 May 9;102(9):1065-74. doi: 10.1161/CIRCRESAHA.107.166124. Epub 2008 Mar 27.
9
Matrix GLA protein, an inhibitory morphogen in pulmonary vascular development.基质γ-羧基谷氨酸蛋白，一种肺血管发育中的抑制性形态发生素。
J Biol Chem. 2007 Oct 12;282(41):30131-42. doi: 10.1074/jbc.M704297200. Epub 2007 Aug 1.
Zotero 插件