Benisty Sivan, Ben-Jacob Eshel, Ariel Gil, Be'er Avraham
Zuckerberg Institute for Water Research, The Jacob Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev, Sede Boqer Campus 84990, Midreshet Ben-Gurion, Israel.
School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel and Center for Theoretical Biological Physics, Rice University, Houston, Texas 77025, USA.
Phys Rev Lett. 2015 Jan 9;114(1):018105. doi: 10.1103/PhysRevLett.114.018105. Epub 2015 Jan 6.
Under sublethal antibiotics concentrations, the statistics of collectively swarming Bacillus subtilis transitions from normal to anomalous, with a heavy-tailed speed distribution and a two-step temporal correlation of velocities. The transition is due to changes in the properties of the bacterial motion and the formation of a motility-defective subpopulation that self-segregates into regions. As a result, both the colonial expansion and the growth rate are not affected by antibiotics. This phenomenon suggests a new strategy bacteria employ to fight antibiotic stress.
在亚致死抗生素浓度下，集体群体运动的枯草芽孢杆菌的统计数据显示其从正常转变为异常，速度分布呈现重尾特征且速度具有两步时间相关性。这种转变是由于细菌运动特性的变化以及形成了一个运动缺陷亚群体，该亚群体自我隔离成不同区域。结果，菌落扩展和生长速率都不受抗生素影响。这一现象表明细菌对抗生素压力采用了一种新策略。
