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[人工合成羟基磷灰石植入物用于人类牙周骨缺损的临床评估。6例术后随访3年以上的研究病例]

[Clinical evaluation of synthetic hydroxyapatite implants for human periodontal osseous defects. 6 cases studied more than 3 years after the surgery].

作者信息

Hotta Y, Kajimoto T, Murahashi Y, Yamamura S, Horiguchi Y, Kajikawa K, Murakami J, Hori T, Mizuno K, Shiraki M

出版信息

Gifu Shika Gakkai Zasshi. 1989 Jun;16(1):278-91.

PMID:2561563
Abstract

We applied of granular hydroxyapatite HAP to periodontal bone defects, for the purpose of restoring the periodontal tissue destroyed by periodontal disease, the subjects were 6 patients (6 regions) with chronic marginal periodontitis who had passed more than 3 years since HAP implantation. After routine periodontal initial treatment, a flap operation was performed, and granular HAP, or a combination of granular and block-like HAP, was implanted into the periodontal bone defect. Clinical parameters were probing depth, clinical attachment level, clinical gingival margin, residual HAP volume and X-ray before operation, at 3, 6, 12 months, and 2, 3, and 4, 6 years after the operation. The results revealed that all measured values showed good results for both granular HAP and the combination of granular and block-like HAP after implantation, and that all cases showed stable results from 12 months on. No remarkable difference was noted between the implanted regions.

摘要

我们将颗粒状羟基磷灰石(HAP)应用于牙周骨缺损,目的是修复因牙周病而破坏的牙周组织。研究对象为6例慢性边缘性牙周炎患者(6个区域),自植入HAP以来已过去3年多。在进行常规牙周初始治疗后,实施翻瓣手术,并将颗粒状HAP或颗粒状与块状HAP的组合植入牙周骨缺损处。临床参数包括术前、术后3个月、6个月、12个月以及术后2年、3年、4年和6年的探诊深度、临床附着水平、临床牙龈边缘、残余HAP体积和X线检查结果。结果显示,植入后颗粒状HAP以及颗粒状与块状HAP组合的所有测量值均显示出良好效果,并且所有病例从12个月起均显示出稳定结果。植入区域之间未发现显著差异。

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