Zareba A, Wisławski J
Kliniki Neurochirurgii Instytutu Chirurgii AM, Warszawie.
Neurol Neurochir Pol. 1989 Jul-Dec;23(4-6):368-72.
Two female patients are described with survival over 13 years after operation for glioblastoma multiforme. The first patient was 42-year-old at the time of partial removal of the tumour situated in deep parts of the temporal lobe. After the operation she was not given any radiotherapy. CT done 13 years after the operation failed to show tumour presence. The patient is leading a self-dependent life (80 points in Karnofski scale). The other female patient was 28-year-old at the time of nearly complete removal (macroscopic) of right temporal lobe tumour. She received cobalt radiotherapy. CT 9 years after the operation showed no tumour. The present state of the patient was evaluated at 90 points Karnofsky scale. In no case cytostatics were given. These cases demonstrate an exceptionally long survival after operation for malignant glioma. The cause of this long survival is not known.
本文描述了两名多形性胶质母细胞瘤患者术后存活超过13年的病例。首例患者在部分切除位于颞叶深部的肿瘤时为42岁。术后未接受任何放疗。术后13年进行的CT检查未显示肿瘤存在。该患者过着自理生活（卡诺夫斯基评分80分）。另一名女性患者在几乎完全切除（肉眼可见）右侧颞叶肿瘤时为28岁。她接受了钴放疗。术后9年的CT检查未显示肿瘤。该患者目前的状态经卡诺夫斯基评分评估为90分。两例患者均未接受过细胞毒性药物治疗。这些病例显示出恶性胶质瘤术后异常长的生存期。这种长生存期的原因尚不清楚。
