Maryniak R, Nasierowska A
Pneumonol Pol. 1989 Oct-Dec;57(10-12):489-95.
Selected neoplastic markers (NSE, gastrin, CEA, calcitonin, keratin) were studied in pulmonary specimens from 5 patients with bronchial carcinoid, 20--with small cell lung cancer (SCLC), and 2 with solid tumors. In patients with carcinoid and SCLC NSE and gastrin markers were found--characteristic for neuroendocrine neoplasia. The author discuss the usefulness of immunohistochemistry in differential diagnostics of pulmonary malignancy.
在5例支气管类癌患者、20例小细胞肺癌(SCLC)患者以及2例实体瘤患者的肺标本中,对选定的肿瘤标志物(神经元特异性烯醇化酶、胃泌素、癌胚抗原、降钙素、角蛋白)进行了研究。在类癌和小细胞肺癌患者中发现了神经元特异性烯醇化酶和胃泌素标志物——这是神经内分泌肿瘤的特征。作者讨论了免疫组织化学在肺恶性肿瘤鉴别诊断中的作用。