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主动脉瓣置换术后并发症预测风险评分的比较

Comparison of Risk Scores for Prediction of Complications following Aortic Valve Replacement.

作者信息

Wang Tom Kai Ming, Choi David Hyun-Min, Haydock David, Gamble Greg, Stewart Ralph, Ruygrok Peter

机构信息

Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand.

Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand.

出版信息

Heart Lung Circ. 2015 Jun;24(6):595-601. doi: 10.1016/j.hlc.2014.11.021. Epub 2014 Dec 12.

Abstract

BACKGROUND

Risk models play an important role in stratification of patients for cardiac surgery, but their prognostic utilities for post-operative complications are rarely studied. We compared the EuroSCORE, EuroSCORE II, Society of Thoracic Surgeon's (STS) Score and an Australasian model (Aus-AVR Score) for predicting morbidities after aortic valve replacement (AVR), and also evaluated seven STS complications models in this context.

METHODS

We retrospectively calculated risk scores for 620 consecutive patients undergoing isolated AVR at Auckland City Hospital during 2005-2012, assessing their discrimination and calibration for post-operative complications.

RESULTS

Amongst mortality scores, the EuroSCORE was the best at discriminating stroke (c-statistic 0.845); the EuroSCORE II at deep sternal wound infection (c=0.748); and the STS Score at composite morbidity or mortality (c=0.666), renal failure (c=0.634), ventilation>24 hours (c=0.732), return to theatre (c=0.577) and prolonged hospital stay >14 days post-operatively (c=0.707). The individual STS complications models had a marginally higher c-statistic (c=0.634-0.846) for all complications except mediastinitis, and had good calibration (Hosmer-Lemeshow test P-value 0.123-0.915) for all complications.

CONCLUSION

The STS Score was best overall at discriminating post-operative complications and their composite for AVR. All STS complications models except for deep sternal wound infection had good discrimination and calibration for post-operative complications.

摘要

背景

风险模型在心脏手术患者分层中发挥着重要作用,但它们对术后并发症的预后效用很少被研究。我们比较了欧洲心脏手术风险评估系统(EuroSCORE)、欧洲心脏手术风险评估系统二代(EuroSCORE II)、胸外科医师协会(STS)评分和一种澳大利亚模型(澳大拉西亚主动脉瓣置换术评分,Aus-AVR Score)预测主动脉瓣置换术(AVR)后发病率的情况,并在此背景下评估了7种STS并发症模型。

方法

我们回顾性计算了2005年至2012年期间在奥克兰市医院连续接受单纯AVR手术的620例患者的风险评分,评估它们对术后并发症的区分度和校准度。

结果

在死亡率评分中,EuroSCORE在区分中风方面表现最佳(c统计量为0.845);EuroSCORE II在区分深部胸骨伤口感染方面最佳(c = 0.748);而STS评分在区分综合发病率或死亡率(c = 0.666)、肾衰竭(c = 0.634)、通气超过24小时(c = 0.732)、返回手术室(c = 0.577)以及术后住院时间延长超过14天(c = 0.707)方面表现最佳。除纵隔炎外,个体STS并发症模型对所有并发症的c统计量略高(c = 0.634 - 0.846),并且对所有并发症具有良好的校准度(Hosmer-Lemeshow检验P值为0.123 - 0.915)。

结论

总体而言,STS评分在区分AVR术后并发症及其综合情况方面表现最佳。除深部胸骨伤口感染外,所有STS并发症模型对术后并发症都具有良好的区分度和校准度。

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