Kern Janet K, Geier David A, Bjørklund Geir, King Paul G, Homme Kristin G, Haley Boyd E, Sykes Lisa K, Geier Mark R
Institute of Chronic Illnesses, Inc., Silver Spring, MD, USA.
Council for Nutritional and Environmental Medicine, Mo i Rana, Norway.
Neuro Endocrinol Lett. 2014;35(7):537-52.
The purpose of this review is to examine the evidence for a relationship between mercury (Hg) exposure from dental amalgams and certain idiopathic chronic illnesses--chronic fatigue syndrome (CFS), fibromyalgia (FM), depression, anxiety, and suicide. Dental amalgam is a commonly used dental restorative material that contains approximately 50% elemental mercury (Hg0) by weight and releases Hg0 vapor. Studies have shown that chronic Hg exposure from various sources including dental amalgams is associated with numerous health complaints, including fatigue, anxiety, and depression--and these are among the main symptoms that are associated with CFS and FM. In addition, several studies have shown that the removal of amalgams is associated with improvement in these symptoms. Although the issue of amalgam safety is still under debate, the preponderance of evidence suggests that Hg exposure from dental amalgams may cause or contribute to many chronic conditions. Thus, consideration of Hg toxicity may be central to the effective clinical investigation of many chronic illnesses, particularly those involving fatigue and depression.
本综述的目的是研究牙科汞合金中汞（Hg）暴露与某些特发性慢性疾病——慢性疲劳综合征（CFS）、纤维肌痛（FM）、抑郁症、焦虑症和自杀之间关系的证据。牙科汞合金是一种常用的牙科修复材料，按重量计含有约50%的元素汞（Hg0）并释放Hg0蒸气。研究表明，包括牙科汞合金在内的各种来源的慢性汞暴露与众多健康问题相关，包括疲劳、焦虑和抑郁——而这些正是与CFS和FM相关的主要症状。此外，多项研究表明，去除汞合金与这些症状的改善有关。尽管汞合金安全性问题仍在争论中，但大量证据表明，牙科汞合金中的汞暴露可能导致或促成许多慢性疾病。因此，考虑汞毒性可能是许多慢性疾病有效临床研究的核心，尤其是那些涉及疲劳和抑郁的疾病。
