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股骨髋臼撞击症临床研究:复合结局是答案吗?

Femoro-acetabular impingement clinical research: is a composite outcome the answer?

作者信息

Ayeni Olufemi R, Sansone Mikael, de Sa Darren, Simunovic Nicole, Bedi Asheesh, Kelly Bryan T, Farrokhyar Forough, Karlsson Jon

机构信息

Division of Orthopaedic Surgery, Department of Surgery, McMaster University Medical Centre, 1200 Main Street West, 4E15, Hamilton, ON, L8N 3Z5, Canada.

Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Sahlgrenska University Hospital/Mölndal, Mölndal, Sweden.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2016 Jan;24(1):295-301. doi: 10.1007/s00167-014-3500-9. Epub 2015 Jan 25.

Abstract

Femoro-acetabular impingement (FAI) is increasingly recognized as an important cause of hip pain in the young adult. However, the methods of evaluating the efficacy of surgical intervention are often not validated and/or inconsistently reported. Important clinical, gait, radiographic and biomarker outcomes are discussed. This article (1) presents the rationale for considering a composite outcome for FAI patients; (2) examines a variety of important end points currently used to evaluate FAI surgery; (3) discusses a strategy to generate a composite outcome by combining these end points; and (4) highlights the challenges and current areas of controversy that such an approach to evaluating symptomatic FAI patients may present.

摘要

股骨髋臼撞击症(FAI)日益被认为是年轻成年人髋关节疼痛的一个重要原因。然而,评估手术干预疗效的方法往往未经验证和/或报告不一致。本文讨论了重要的临床、步态、影像学和生物标志物结果。本文(1)阐述了考虑为FAI患者采用综合结局指标的基本原理;(2)审视了目前用于评估FAI手术的各种重要终点;(3)讨论了通过组合这些终点来生成综合结局指标的策略;(4)强调了这种评估有症状FAI患者方法可能带来的挑战和当前存在争议的领域。

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