Daiichi University of Pharmacy, Tamagawa-cho, Minami-ku, Fukuoka 815-8511, Japan.
Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Yoshida Konoe, Sakyo, Kyoto 606-8501, Japan.
Environ Pollut. 2015 Apr;199:35-41. doi: 10.1016/j.envpol.2015.01.007. Epub 2015 Jan 22.
This study investigates perfluoroalkyl carboxylic acids (PFCAs) contamination of edible fish muscle from Japanese coastal waters. The concentrations of PFCAs with 8-14 carbon atoms (C8-C14) in Pacific cods in Hokkaido, Japan were 51 (median: pg/g-wet weight) for C8, 93 for C9, 99 for C10, 746 for C11, 416 for C12, 404 for C13, and 93 for C14. The levels of C9-C14 PFCAs in fish were strongly correlated to each other, but not to C8 and the other chlorinated persistent organic pollutants, indicating that C9-C14 PFCAs have a different emission source and/or bioaccumulation mechanism. The relative ratios between estimated PFCAs intake through fish consumption and the reported total dietary exposure of PFCAs were less than 1 for C8 to C9, but were more than 1 for C10 to C14. This result strongly suggests that fish consumption is a significant source of human dietary exposure to C10-C14 PFCAs.
本研究调查了来自日本沿海海域食用鱼类肌肉中的全氟羧酸（PFCAs）污染情况。在日本北海道的太平洋鳕鱼中，8-14 个碳原子（C8-C14）的 PFCAs 浓度分别为：C8 为 51（中位数：pg/g-湿重）、C9 为 93、C10 为 99、C11 为 746、C12 为 416、C13 为 404、C14 为 93。鱼体内的 C9-C14 PFCAs 水平彼此之间呈强相关性，但与 C8 和其他氯化持久性有机污染物无相关性，这表明 C9-C14 PFCAs 具有不同的排放源和/或生物累积机制。通过鱼类消费摄入的估计 PFCAs 与报告的 PFCAs 总膳食暴露量之间的相对比例，对于 C8 到 C9 小于 1，但对于 C10 到 C14 则大于 1。这一结果强烈表明，鱼类消费是人类膳食中 C10-C14 PFCAs 暴露的重要来源。
