使用环糊精-二氧化硅杂化微孔复合采样器测定空气中的酚类化合物。

Determination of phenolic compounds in air by using cyclodextrin-silica hybrid microporous composite samplers.

作者信息

Mauri-Aucejo Adela R, Ponce-Català Patricia, Belenguer-Sapiña Carolina, Amorós Pedro

机构信息

Departament de Química Analítica, Facultat de Química, Universitat de València, Dr Moliner 50, Burjassot, 46100 València, Spain.

出版信息

Talanta. 2015 Mar;134:560-567. doi: 10.1016/j.talanta.2014.11.057. Epub 2014 Dec 2.

DOI:10.1016/j.talanta.2014.11.057

PMID:25618708

Abstract

An analytical method for the determination of phenolic compounds in air samples based on the use of cyclodextrin-silica hybrid microporous composite samplers is proposed. The method allows the determination of phenol, guaiacol, cresol isomers, eugenol, 4-ethylphenol and 4-ethylguaiacol in workplaces according to the Norm UNE-EN 1076:2009 for active sampling. Therefore, the proposed method offers an alternative for the assessment of the occupational exposure to phenol and cresol isomers. The detection limits of the proposed method are lower than those for the NIOSH Method 2546. Storage time of samples almost reaches 44 days. Recovery values for phenol, guaiacol, o-cresol, m-cresol, p-cresol, 4-ethylguaiacol, eugenol and 4-ethylphenol are 109%, 99%, 102%, 94%, 94%, 91%, 95% and 102%, respectively with a coefficient of variation below 6%. The method has been applied to the assessment of exposure in different areas of a farm and regarding the quantification of these compounds in the vapors generated by burning incense sticks and an essential oil marketed as air fresheners. The acquired results are comparable with those provided from a reference method for a 95% of confidence level. The possible use of these samplers for the sampling of other toxic compounds such as phthalates is evaluated by qualitative analysis of extracts from incense sticks and essential oil samples.

摘要

提出了一种基于使用环糊精-二氧化硅杂化微孔复合采样器测定空气样品中酚类化合物的分析方法。该方法可根据UNE-EN 1076:2009标准进行工作场所空气中苯酚、愈创木酚、甲酚异构体、丁香酚、4-乙基苯酚和4-乙基愈创木酚的主动采样测定。因此，该方法为评估职业接触苯酚和甲酚异构体提供了一种替代方法。该方法的检测限低于美国国家职业安全与健康研究所（NIOSH）方法2546的检测限。样品的储存时间几乎达到44天。苯酚、愈创木酚、邻甲酚、间甲酚、对甲酚、4-乙基愈创木酚、丁香酚和4-乙基苯酚的回收率分别为109%、99%、102%、94%、94%、91%、95%和102%，变异系数低于6%。该方法已应用于评估农场不同区域的暴露情况，以及对香薰棒和作为空气清新剂销售的香精油燃烧产生的蒸汽中这些化合物的定量分析。在95%的置信水平下，所获得的结果与参考方法提供的结果具有可比性。通过对香薰棒和香精油样品提取物的定性分析，评估了这些采样器用于其他有毒化合物（如邻苯二甲酸盐）采样的可能性。