Opioid peptides. Partially modified retro-inverso dermorphin analogues. XIII.
作者信息
Marastoni M, Balboni G, Tomatis R, Salvadori S, Borea P A, Uccelli L
机构信息
Dipartimento di Scienze Farmaceutiche, Università di Ferrara, Italy.
出版信息
Farmaco. 1989 Nov;44(11):1083-93.
PMID:2562001
Abstract
We studied the effect of partial retro-inverso modification of a selected peptide bond of dermorphin (H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2) related peptides. The drastic loss of mu-receptor affinity following introduction of retro-inverso peptide bond between Phe1-D-Ala2 in the new peptide analogues, emphasized the importance of this backbone in the dermorphin peptides.
摘要
Zotero 插件