• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用口服药物管理妊娠期糖尿病:我们学到了什么?

Using oral agents to manage gestational diabetes: what have we learned?

作者信息

Buschur Elizabeth, Brown Florence, Wyckoff Jennifer

机构信息

University of Michigan, 24 Frank Lloyd Wright Drive, Ann Arbor, MI, 48105, USA,

出版信息

Curr Diab Rep. 2015 Feb;15(2):570. doi: 10.1007/s11892-014-0570-5.

DOI:10.1007/s11892-014-0570-5
PMID:25620403
Abstract

Insulin has been the mainstay of treatment of diabetes during pregnancy for decades. Although glyburide and metformin are classified as category B during pregnancy, recent research has suggested that these oral agents alone or in conjunction with insulin may be safe for the treatment of gestational diabetes (GDM). This paper summarizes the data on the use of glyburide and metformin for treatment of GDM.

摘要

几十年来,胰岛素一直是孕期糖尿病治疗的主要手段。虽然格列本脲和二甲双胍在孕期被归类为B类药物,但最近的研究表明,这些口服药物单独使用或与胰岛素联合使用可能对治疗妊娠期糖尿病(GDM)是安全的。本文总结了关于使用格列本脲和二甲双胍治疗GDM的数据。

相似文献

1
Using oral agents to manage gestational diabetes: what have we learned?使用口服药物管理妊娠期糖尿病:我们学到了什么?
Curr Diab Rep. 2015 Feb;15(2):570. doi: 10.1007/s11892-014-0570-5.
2
Benefits and risks of oral diabetes agents compared with insulin in women with gestational diabetes: a systematic review.妊娠糖尿病女性中口服降糖药与胰岛素相比的益处和风险:一项系统评价
Obstet Gynecol. 2009 Jan;113(1):193-205. doi: 10.1097/AOG.0b013e318190a459.
3
Comparative efficacy and safety of oral antidiabetic drugs and insulin in treating gestational diabetes mellitus: An updated PRISMA-compliant network meta-analysis.口服抗糖尿病药物与胰岛素治疗妊娠期糖尿病的疗效和安全性比较:一项更新的符合PRISMA标准的网状Meta分析。
Medicine (Baltimore). 2017 Sep;96(38):e7939. doi: 10.1097/MD.0000000000007939.
4
Oral hypoglycaemic agents during pregnancy: The evidence for effectiveness and safety.孕期口服降糖药:有效性和安全性的证据。
Best Pract Res Clin Obstet Gynaecol. 2011 Feb;25(1):51-63. doi: 10.1016/j.bpobgyn.2010.10.018. Epub 2011 Jan 19.
5
Gestational diabetes mellitus management with oral hypoglycemic agents.口服降糖药治疗妊娠期糖尿病
Semin Perinatol. 2014 Dec;38(8):508-15. doi: 10.1053/j.semperi.2014.08.012. Epub 2014 Oct 12.
6
Oral hypoglycemic agents in pregnancy.妊娠期口服降糖药物。
Obstet Gynecol Clin North Am. 2011 Jun;38(2):227-34, ix. doi: 10.1016/j.ogc.2011.02.013.
7
Perinatal outcomes and the use of oral hypoglycemic agents.围产期结局与口服降糖药的使用
J Perinat Med. 2005;33(6):519-23. doi: 10.1515/JPM.2005.092.
8
Comparison of glyburide with metformin in treating gestational diabetes mellitus: a systematic review and meta-analysis.格列本脲与二甲双胍治疗妊娠期糖尿病的比较:一项系统评价和荟萃分析。
Clin Drug Investig. 2015 Jun;35(6):343-51. doi: 10.1007/s40261-015-0289-3.
9
Oral Agents for the Treatment of Gestational Diabetes.口服药物治疗妊娠期糖尿病。
Curr Diab Rep. 2018 Sep 28;18(11):119. doi: 10.1007/s11892-018-1093-2.
10
Comparative efficacy and safety of OADs in management of GDM: network meta-analysis of randomized controlled trials.口服抗糖尿病药物治疗妊娠期糖尿病的疗效与安全性比较:随机对照试验的网状Meta分析
J Clin Endocrinol Metab. 2015 May;100(5):2071-80. doi: 10.1210/jc.2014-4403. Epub 2015 Mar 24.

引用本文的文献

1
Effect of Glyburide vs Subcutaneous Insulin on Perinatal Complications Among Women With Gestational Diabetes: A Randomized Clinical Trial.二甲双胍对比皮下胰岛素治疗妊娠期糖尿病患者围产期并发症的效果:一项随机临床试验。
JAMA. 2018 May 1;319(17):1773-1780. doi: 10.1001/jama.2018.4072.
2
Oral Medications for Diabetes in Pregnancy: Use in a Rural Population.孕期糖尿病的口服药物:在农村人口中的应用
Diabetes Spectr. 2016 May;29(2):98-101. doi: 10.2337/diaspect.29.2.98.

本文引用的文献

1
First-trimester exposure to metformin and risk of birth defects: a systematic review and meta-analysis.早孕期暴露于二甲双胍与出生缺陷风险:系统评价和荟萃分析。
Hum Reprod Update. 2014 Sep-Oct;20(5):656-69. doi: 10.1093/humupd/dmu022. Epub 2014 May 25.
2
Trends in glyburide compared with insulin use for gestational diabetes treatment in the United States, 2000-2011.美国 2000-2011 年妊娠期糖尿病治疗中格列美脲与胰岛素使用趋势比较。
Obstet Gynecol. 2014 Jun;123(6):1177-1184. doi: 10.1097/AOG.0000000000000285.
3
Expansion of a PBPK model to predict disposition in pregnant women of drugs cleared via multiple CYP enzymes, including CYP2B6, CYP2C9 and CYP2C19.
扩展一个生理药代动力学(PBPK)模型,以预测通过多种细胞色素P450(CYP)酶(包括CYP2B6、CYP2C9和CYP2C19)清除的药物在孕妇体内的处置情况。
Br J Clin Pharmacol. 2014 Mar;77(3):554-70. doi: 10.1111/bcp.12207.
4
Glyburide as treatment option for gestational diabetes mellitus.格列本脲作为妊娠期糖尿病的治疗选择。
J Obstet Gynaecol Res. 2013 Jun;39(6):1147-52. doi: 10.1111/jog.12042. Epub 2013 May 30.
5
Comparison of newborn outcomes in women with gestational diabetes mellitus treated with metformin or insulin: a randomised blinded trial.二甲双胍或胰岛素治疗妊娠期糖尿病女性的新生儿结局比较:一项随机双盲试验
Int J Prev Med. 2013 Mar;4(3):327-33.
6
Retrospective cohort study comparing neonatal outcomes of women treated with glyburide or insulin in gestational diabetes: a 5-year experience in a South Indian teaching hospital.一项回顾性队列研究:比较妊娠糖尿病患者接受格列本脲或胰岛素治疗后的新生儿结局——印度南部一家教学医院的5年经验
Indian J Med Sci. 2011 Nov;65(11):476-81.
7
Metformin compared with insulin in the treatment of pregnant women with overt diabetes: a randomized controlled trial.二甲双胍与胰岛素治疗显性糖尿病孕妇的随机对照试验。
Am J Perinatol. 2013 Jun;30(6):483-90. doi: 10.1055/s-0032-1326994. Epub 2012 Oct 24.
8
Placental drug transporters and their role in fetal protection.胎盘药物转运体及其在胎儿保护中的作用。
Placenta. 2012 Mar;33(3):137-42. doi: 10.1016/j.placenta.2012.01.008. Epub 2012 Jan 20.
9
Management of diabetes in pregnancy.妊娠糖尿病管理。
Curr Diab Rep. 2012 Feb;12(1):33-42. doi: 10.1007/s11892-011-0249-0.
10
Introduction of metformin for gestational diabetes mellitus in clinical practice: Has it had an impact?临床实践中二甲双胍用于妊娠糖尿病的介绍:它产生影响了吗?
Eur J Obstet Gynecol Reprod Biol. 2012 Feb;160(2):147-50. doi: 10.1016/j.ejogrb.2011.11.018. Epub 2011 Dec 3.