Cebrat E, Wegrzyn T, Zieba D, Leroch Z
Katedra Fizjologii Zwierzat Wydziału Weterynaryjnego AR we Wrocławiu.
Pol Arch Weter. 1989;29(3-4):71-8.
The receptors involved in dopamine effect on the motility of the ileum were studied. The experiments were carried out on 3 sheep with chronic fistulas of the ileum and rumen. The contractions of the fistulated parts of the alimentary tract were recorded by the balloon method. Dopamine infused intravenously at a rate 28-38 micrograms.kg-1.min-1 inhibited the motility of the ileum. Domperidone (0.4-0.8 mg.kg-1) did not abolish this inhibiting influence of dopamine. Dopamine infused after propranolol (0.5-0.7 mg.kg-1) inhibited the motility of the ileum, however administrated after phentolamine (0.6-0.8 mg.kg-1) did not change its movements. It has been concluded that dopamine inhibits the ileum motility in sheep through alpha-adrenergic receptors.
研究了多巴胺对回肠运动产生影响所涉及的受体。实验在3只患有回肠和瘤胃慢性瘘管的绵羊身上进行。通过气囊法记录消化道瘘管部位的收缩情况。以28 - 38微克·千克⁻¹·分钟⁻¹的速率静脉输注多巴胺可抑制回肠运动。多潘立酮（0.4 - 0.8毫克·千克⁻¹）不能消除多巴胺的这种抑制作用。在普萘洛尔（0.5 - 0.7毫克·千克⁻¹）之后输注多巴胺可抑制回肠运动，然而在酚妥拉明（0.6 - 0.8毫克·千克⁻¹）之后给药则不会改变其运动。得出的结论是，多巴胺通过α - 肾上腺素能受体抑制绵羊的回肠运动。
