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深部颈部感染的治疗与预后

Treatment and prognosis of deep neck infections.

作者信息

Motahari Seyyed Jafar, Poormoosa Rostam, Nikkhah Mehdi, Bahari Milad, Shirazy Seyyed Mohsen Hosseini, Khavarinejad Freshteh

机构信息

Department of Otolaryngology, Mazandaran University of Medical Sciences, Sari, Iran.

Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

出版信息

Indian J Otolaryngol Head Neck Surg. 2015 Mar;67(Suppl 1):134-7. doi: 10.1007/s12070-014-0802-7. Epub 2014 Nov 27.

Abstract

Deep neck infections could have serious threats for life of patients, if not noticed adequately. Early diagnosis and correct treatment planning can save the patient's lives and prevent complications of disease extension and also surgical procedures that in some instances may be performed in an emergent situation with higher complication rates. Herein, we have studied 815 cases of deep neck abscesses and infections with especial consideration to treatment and prognosis. In a retrospective case review, we studied 815 cases admitted in our medical center from 1998 until the year 2013. Only patients with abscesses or infections deeper than superficial layer of deep cervical fascia were included in this study, based on the review of their medical records. From 815 cases (485 males and 330 females) surgery was indicated and performed in 428 cases and the rest were treated medically. In cases with dental infections as the etiologic factor, dental procedures were performed as early as possible (extraction in almost all cases). Tracheostomy was performed in five cases. All of the patients in medical treatment group and most of the surgically managed patients were discharged while were stable with relative or complete resolution of their symptoms. One of our patients, a 15 year old boy died with symptoms suggestive for mediastinitis and air way compromise. Early diagnosis and medical management can be effective in treating deep neck infections. Dental infections and also procedures are the major cause in our patients, although tonsillitis and peritonsillar abscess also were important leading causes with almost equal numbers in our series. Extraction of the infected tooth as early as possible while medical treatment is continued can be very helpful. In some cases it may be necessary to perform surgical exploration of the neck more than once, and finally, malignant neoplasia, somewhere in the head and neck should be considered in some cases, as in one of our patients with left side submandibular abscess whose underlying disorder was tongue SCC with neck metastasis. Prognosis can be excellent in both medically and surgically managed groups if started and designed early and promptly.

摘要

深部颈部感染若未得到充分重视,可能会对患者生命构成严重威胁。早期诊断和正确的治疗方案能够挽救患者生命,预防疾病蔓延引发的并发症,以及避免在某些紧急情况下进行的、并发症发生率较高的外科手术。在此,我们研究了815例深部颈部脓肿和感染病例,并特别关注了治疗和预后情况。在一项回顾性病例分析中,我们研究了1998年至2013年期间在我们医疗中心收治的815例患者。根据病历审查,本研究仅纳入了深部颈筋膜浅层以下存在脓肿或感染的患者。815例患者(485例男性和330例女性)中,428例患者接受了手术治疗,其余患者接受药物治疗。对于以牙齿感染为病因的病例,尽早进行牙科治疗(几乎所有病例均进行了拔牙)。5例患者进行了气管切开术。药物治疗组的所有患者以及大多数接受手术治疗的患者在症状相对或完全缓解且病情稳定后出院。我们的一名患者,一名15岁男孩,因纵隔炎和气道受压症状死亡。早期诊断和药物治疗对于深部颈部感染的治疗可能有效。牙齿感染及其治疗是我们患者中的主要病因,尽管扁桃体炎和扁桃体周围脓肿在我们的病例系列中也是重要的主要病因,且数量几乎相同。在持续药物治疗的同时尽早拔除感染牙齿可能非常有帮助。在某些情况下,可能需要不止一次地对颈部进行手术探查,最后,在某些情况下应考虑头颈部某处存在恶性肿瘤,例如我们的一名左侧颌下脓肿患者,其潜在疾病为舌鳞状细胞癌伴颈部转移。如果早期及时开始并设计合理的治疗方案,药物治疗组和手术治疗组的预后都可能非常好。

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