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[颈部深部感染:95例临床分析]

[Deep neck infection: clinical analyses of 95 cases].

作者信息

Cheng Zexing, Yu Juebo, Xiao Lu, Lian Zhuang, Wei Yiling, Wang Junfeng

机构信息

Department of Otorhinolaryngology, Yangzhou First People's Hospital, Yangzhou 225001, China.

Department of Otorhinolaryngology, Yangzhou First People's Hospital, Yangzhou 225001, China; Email:

出版信息

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Sep;50(9):769-72.

Abstract

OBJECTIVE

To review the recent diagnosis and treatment experience with deep neck infection and emphasize the importance of radiologic evaluation, microbiology and appropriate treatment selection in these patients.

METHODS

A respective review was conducted in 95 cases who were diagnosed as having deep neck from Jan. 2006 to March 2015.

RESULTS

The primary diseases in 95 patients with deep neck infection were acute tonsillitis or acute laryngitis (27 cases), infection of upper respiratory tract (23 cases), odontogenic infection or oral inflammation (16 cases), foreign bodies in esophagus (9 cases), acute cervical lymphadenitis (5 cases) and cause uncertain (15 cases). Computed tomography was performed in all of patients to identify the location, extent, and character (cellulitis in 47 cases or abscesses in 48 cases) of the infections. The locations of abscess were parapharyngeal abscess (25 cases), retropharyngeal abscess (9 cases), submaxillary space abscess (6 cases), pretracheal space abscess (5 cases) and esophageal abscess (3 cases).

COMPLICATIONS

mediastinitis (2 cases), pericarditis (1 case), bilateral pneumothorax (2 cases), and upper digestive tract (1 case). Bacterial cultivation performed in 35 patients and positive results were detected in 21. All patients were given intravenous antibiotic therapy. Tracheotomy was performed in 4 cases. Preoperative contrast enhanced CT was performed in 42 patients and indicated the formation of abscess. Three cases with the symptoms of septic shock were transferred to ICU and one was cured. All the patients were cured except two who died of massive hemorrhage of upper digestive tract and septic shock.

CONCLUSIONS

The airway patency in patients with deep neck infections must be ensured. Drainage may be mandatory in selected cases at presentation or in cases who fail to respond to parenteral antibiotics within the first 24-48 hours. Imaging evaluation plays a significant role in the diagnosis and rational therapeutic management in deep neck infection. Bacterial cultivation can help to make the effective treatment and provide reliable evidence for the etiopathogenisis.

摘要

目的

回顾近期深部颈部感染的诊断与治疗经验,并强调影像学评估、微生物学检查及恰当治疗选择在这些患者中的重要性。

方法

对2006年1月至2015年3月期间诊断为深部颈部感染的95例患者进行回顾性分析。

结果

95例深部颈部感染患者的原发疾病包括急性扁桃体炎或急性喉炎(27例)、上呼吸道感染(23例)、牙源性感染或口腔炎症(16例)、食管异物(9例)、急性颈淋巴结炎(5例)及病因不明(15例)。所有患者均行计算机断层扫描以确定感染的部位、范围及特征(蜂窝织炎47例,脓肿48例)。脓肿部位包括咽旁脓肿(25例)、咽后脓肿(9例)、颌下间隙脓肿(6例)、气管前间隙脓肿(5例)及食管脓肿(3例)。

并发症

纵隔炎(2例)、心包炎(1例)、双侧气胸(2例)及上消化道病变(1例)。35例患者进行了细菌培养,21例检测出阳性结果。所有患者均接受静脉抗生素治疗。4例行气管切开术。42例患者术前行增强CT检查,提示脓肿形成。3例出现感染性休克症状的患者转入重症监护病房,1例治愈。除2例因上消化道大出血和感染性休克死亡外,所有患者均治愈。

结论

必须确保深部颈部感染患者的气道通畅。在某些就诊时的病例或在最初24 - 48小时内对肠外抗生素治疗无反应的病例中,引流可能是必要的。影像学评估在深部颈部感染的诊断和合理治疗管理中起着重要作用。细菌培养有助于进行有效治疗,并为病因学提供可靠证据。

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