Colditz I G, Cox T, Small A H
CSIRO FD McMaster Laboratory, Locked Bag 1, Delivery Centre, Armidale, New South Wales, 2350, Australia.
Aust Vet J. 2015 Jan-Feb;93(1-2):31-5. doi: 10.1111/avj.12282.
To assess whether human laser epilation technology can permanently prevent wool growth in sheep.
An observational study.
Two commercial human epilation lasers (Sharplan alexandrite 755 nm laser, and Lumenis LightSheer 800 nm diode laser) were tested at energies between 10 and 100 J/cm2 and pulse widths from 2 to 400 ms. Wool was clipped from flank, breech, pizzle and around the eyes of superfine Merino sheep with Oster clippers. After initial laser removal of residual wool to reveal bare skin, individual skin sites were treated with up to 15 cycles of laser irradiation. Behavioural responses during treatment, skin temperature immediately after treatment and skin and wool responses for 3 months after treatment were monitored.
A clear transudate was evident on the skin surface within minutes. A dry superficial scab developed by 24 h and remained adherent for at least 6 weeks. When scabs were shed, there was evidence of scarring at sites receiving multiple treatment cycles and normal wool growth in unscarred skin. There was no evidence of laser energy level or pulse width affecting the response of skin and wool to treatment and no evidence of permanent inhibition of wool growth by laser treatment. Laser treatment was well tolerated by the sheep.
Treatment of woolled skin with laser parameters that induce epilation by selective photothermolysis in humans failed to induce permanent inhibition of wool growth in sheep. Absence of melanin in wool may have contributed to the result.
评估人类激光脱毛技术能否永久性阻止绵羊毛发的生长。
一项观察性研究。
对两款商用的人类脱毛激光器(Sharplan翠绿宝石755纳米激光器和Lumenis LightSheer 800纳米二极管激光器)进行测试,能量范围为10至100焦耳/平方厘米,脉冲宽度为2至400毫秒。使用奥斯特剪毛器从超细美利奴绵羊的胁腹、臀部、阴茎和眼睛周围剪下羊毛。在最初用激光去除残留羊毛以露出裸露皮肤后,对各个皮肤部位进行多达15个周期的激光照射。监测治疗期间的行为反应、治疗后立即的皮肤温度以及治疗后3个月的皮肤和羊毛反应。
数分钟内皮肤表面出现明显的渗出液。24小时后形成干燥的浅表结痂,且至少持续附着6周。当痂皮脱落时,接受多个治疗周期的部位有瘢痕形成的迹象,而未形成瘢痕的皮肤处羊毛正常生长。没有证据表明激光能量水平或脉冲宽度会影响皮肤和羊毛对治疗的反应,也没有证据表明激光治疗能永久性抑制羊毛生长。绵羊对激光治疗耐受性良好。
采用在人类中通过选择性光热解诱导脱毛的激光参数治疗有毛皮肤,未能在绵羊中诱导出对羊毛生长的永久性抑制。羊毛中缺乏黑色素可能是导致该结果的原因。