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生长马眼的中央角膜厚度测量及超声检查研究

Central corneal thickness measurements and ultrasonographic study of the growing equine eye.

作者信息

Herbig Lena E, Eule J Corinna

机构信息

Small Animal Clinic, Freie Universität Berlin, Oertzenweg 19b, 14163, Berlin, Germany.

出版信息

Vet Ophthalmol. 2015 Nov;18(6):462-71. doi: 10.1111/vop.12252. Epub 2015 Jan 27.

DOI:10.1111/vop.12252
PMID:25623263
Abstract

OBJECTIVE

The aim of this study was to determine the central corneal thickness (CCT) of healthy equine eyes with high-frequency ultrasound (HF) and ultrasound biomicroscopy (UBM) and to measure the axial dimensions with B-mode ultrasound. Additionally, the influence of the age on the measured dimensions of the globe was analyzed.

ANIMALS STUDIED

Fifty warm blood horses (mean age 23.0 ± 21.12 months) were divided into 3 age groups (group 1: 0-6 months; group 2: ≥7-30 months; and group 3: ≥31-78 months).

PROCEDURE

Corneal measurements were performed with a 22-MHz and a 50-MHz transducer. Crystalline lens thickness (CLT), vitreous chamber depth (VCD), and axial globe length (AGL) were measured at a frequency of 10 MHz. Anterior chamber depth (ACD) was calculated. The eyes were measured under general anesthesia nonrelated to this study.

RESULTS

The mean CCT of 50 eyes was 818 ± 41 μm. The mean values ± SD in mm for axial dimensions were AGL 34.7 ± 2.7, ACD 3.4 ± 0.7, CLT 10.0 ± 0.9, and VCD of 20.4 ± 1.5. A positive correlation with increasing age was found for all dimensions. No significant differences were found between the gender and the left or right eye.

CONCLUSION

HF and UBM are valuable high-resolution imaging tools for CCT measurements in horses. The here-obtained values support previous findings that a positive correlation with increasing age exists for CCT, ACD, CLT, VCD, and AGL in horse.

摘要

目的

本研究旨在使用高频超声(HF)和超声生物显微镜(UBM)测定健康马眼的中央角膜厚度(CCT),并使用B型超声测量眼轴尺寸。此外,分析年龄对所测眼球尺寸的影响。

研究动物

50匹温血马(平均年龄23.0±21.12个月)被分为3个年龄组(第1组:0 - 6个月;第2组:≥7 - 30个月;第3组:≥31 - 78个月)。

方法

使用22MHz和50MHz的探头进行角膜测量。在10MHz频率下测量晶状体厚度(CLT)、玻璃体腔深度(VCD)和眼轴长度(AGL)。计算前房深度(ACD)。在与本研究无关的全身麻醉下对眼睛进行测量。

结果

50只眼睛的平均CCT为818±41μm。眼轴尺寸的平均值±标准差(单位:mm)为AGL 34.7±2.7、ACD 3.4±0.7、CLT 10.0±0.9、VCD 20.4±1.5。所有尺寸均与年龄增长呈正相关。性别和左右眼之间未发现显著差异。

结论

HF和UBM是用于测量马CCT的有价值的高分辨率成像工具。此处获得的值支持先前的研究结果,即马的CCT、ACD、CLT、VCD和AGL与年龄增长呈正相关。

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