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预计阴道内射精潜伏时间能否与秒表测量的阴道内射精潜伏时间互换用于诊断终身性早泄?

Can estimated intravaginal ejaculatory latency time be used interchangeably with stopwatch-measured intravaginal ejaculatory latency time for the diagnosis of lifelong premature ejaculation?

机构信息

Department of Urology, College of Medicine, Chuncheon Sacred Heart Hospital, Hallym University, Chuncheon Korea.

Kangnam Sacred Heart Hospital, Seoul, Korea.

出版信息

Urology. 2015 Feb;85(2):375-80. doi: 10.1016/j.urology.2014.09.036.

DOI:10.1016/j.urology.2014.09.036
PMID:25623693
Abstract

OBJECTIVE

To examine the correlation between estimated intravaginal ejaculatory latency time (eIELT) and stopwatch-measured intravaginal ejaculatory latency time (sIELT), and to assess the clinical utility of eIELT in identifying men more likely to have lifelong premature ejaculation (PE).

METHODS

A prospective, observational, multicenter study was conducted. Between July 2010 and August 2011, 118 healthy men aged 30-70 years, more likely to have lifelong PE, were recruited from 5 institutions in Korea. All patients underwent preliminary assessments including collection of medical and sexual history, physical examination, determination of eIELT, and the Premature Ejaculation Profile questionnaire. During the 1-week study period, patients were requested to engage in sexual intercourse at least twice and to record the sIELT.

RESULTS

eIELT and sIELT correlated well (r = 0.512; P < .001). However, eIELT was overestimated by a mean of 1.2 ± 0.2 minutes (median, 1.0 minutes) compared with sIELT (P = .046). eIELT showed a reduced correlation with the Premature Ejaculation Profile measures, compared with sIELT (each P-value < .05). The diagnostic accuracy of eIELT was 67.9% (P = .001), and an eIELT of 2 minutes was the acceptable cutoff value to diagnose lifelong PE.

CONCLUSION

Although eIELT correlated well with sIELT, it was overestimated by approximately 1 minute and had lower clinical utility than sIELT. Our study suggests that eIELT and sIELT cannot be directly interchanged and that caution should be used when substituting sIELT with eIELT to identify men who are more likely to have lifelong PE.

摘要

目的

探讨估计阴道内射精潜伏时间(eIELT)与秒表测量阴道内射精潜伏时间(sIELT)之间的相关性,并评估 eIELT 在识别更可能患有终身早泄(PE)的男性中的临床应用价值。

方法

进行了一项前瞻性、观察性、多中心研究。2010 年 7 月至 2011 年 8 月,从韩国的 5 个机构招募了 118 名年龄在 30-70 岁之间、更可能患有终身 PE 的健康男性。所有患者均接受初步评估,包括采集病史和性生活史、体格检查、eIELT 测定和早泄评估问卷。在为期 1 周的研究期间,要求患者至少进行 2 次性行为,并记录 sIELT。

结果

eIELT 和 sIELT 相关性良好(r=0.512;P<0.001)。然而,与 sIELT 相比,eIELT 平均高估了 1.2±0.2 分钟(中位数为 1.0 分钟)(P=0.046)。与 sIELT 相比,eIELT 与早泄评估问卷的相关性降低(P 值均<0.05)。eIELT 的诊断准确性为 67.9%(P=0.001),将 eIELT 设定为 2 分钟作为诊断终身 PE 的可接受截断值。

结论

尽管 eIELT 与 sIELT 相关性良好,但它被高估了约 1 分钟,临床应用价值低于 sIELT。我们的研究表明,eIELT 和 sIELT 不能直接互换,在使用 eIELT 替代 sIELT 来识别更可能患有终身 PE 的男性时应谨慎。

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