Smith N A, Chakraverty R K, Obeid D, Boughton B J
Department of Haematology, Queen Elizabeth Hospital, Edgbaston, Birmingham.
Autoimmunity. 1989;4(1-2):115-7. doi: 10.3109/08916938909034366.
A patient with chronic ITP relapsed after conventional therapy but following an infusion with low dose anti D (Rho) immunoglobulin, she entered a remission which has now lasted 10 months. This is difficult to explain on the basis of long term macrophage Fc receptor blockade and suggests an alternative mechanism of action.
一名慢性免疫性血小板减少症(ITP)患者在接受传统治疗后复发,但在输注低剂量抗D(Rho)免疫球蛋白后进入缓解期,目前已持续10个月。这很难基于长期巨噬细胞Fc受体阻断来解释,提示存在另一种作用机制。