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用于胸腺癌的节拍化疗

Metronomics for thymic carcinoma.

作者信息

Del Toro Jacobo Muñoz, Castedo Patricia Cortez, Salgado Alfonso Cortés, García M Eugenia Olmedo, López Pilar Garrido

机构信息

Medical Oncology Department, Hospital Universitario Ramón y Cajal, Ctra de Colmenar Viejo km 9, Madrid 28034, Spain.

出版信息

Ecancermedicalscience. 2014 Dec 18;8:494. doi: 10.3332/ecancer.2014.494. eCollection 2014.

Abstract

Although thymomas are the most frequent primary tumours of the anterior mediastinum, thymic carcinoma is very infrequent and more aggressive. Combination chemotherapy is the first-line treatment for the advanced stages, but because of the lack of evidence from randomised trials, the management of the successive lines is a challenging field. We report a partial radiological response in the seventh line of a thymic carcinoma stage IV with an oral regimen.

摘要

虽然胸腺瘤是前纵隔最常见的原发性肿瘤,但胸腺癌非常罕见且侵袭性更强。联合化疗是晚期患者的一线治疗方法,但由于缺乏随机试验证据,后续治疗方案的选择是一个具有挑战性的领域。我们报告了1例IV期胸腺癌患者口服方案进行第七线治疗时出现部分影像学缓解的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7ce/4303607/d5809cbabaf6/can-8-494fig1.jpg

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