Zhao Lianjun, Yan Jing, Li Li, Wei Jia, Li Lin, Qian Xiaoping, Liu Baorui, Zou Zhengyun
Comprehensive Cancer Center of Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Comprehensive Cancer Center of Nanjing Drum Tower Hospital, Medical School and Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu 210008, P.R. China.
Oncol Lett. 2015 Feb;9(2):609-613. doi: 10.3892/ol.2014.2745. Epub 2014 Nov 28.
Clinical reports of primary sphenoid sinus melanoma and isolated gastric metastatic melanoma are rare. Thus, to the best of our knowledge, the present study reports the first case of isolated gastric metastasis from a sphenoid sinus melanoma. The aim of the present study was to discuss the clinicopathological and radiographic characteristics, the treatment strategy and the prognosis of sphenoid sinus metastatic malignant melanoma of the stomach. Although almost 60% of patients who succumb to melanoma exhibit gastrointestinal metastases at autopsy, antemortem diagnosis is uncommon; this is predominantly due to gastric metastatic melanoma presenting with non-specific symptoms similar to other common gastrointestinal diseases. Gastrectomy may prolong overall survival and improve the quality of life for gastric metastatic melanoma patients, and the present case emphasizes the importance of palliative surgery in such cases.
原发性蝶窦黑色素瘤和孤立性胃转移性黑色素瘤的临床报告很少见。因此，据我们所知，本研究报告了首例来自蝶窦黑色素瘤的孤立性胃转移病例。本研究的目的是探讨胃蝶窦转移性恶性黑色素瘤的临床病理和影像学特征、治疗策略及预后。尽管近60%死于黑色素瘤的患者在尸检时显示有胃肠道转移，但生前诊断并不常见；这主要是因为胃转移性黑色素瘤表现出与其他常见胃肠道疾病相似的非特异性症状。胃切除术可能会延长胃转移性黑色素瘤患者的总生存期并改善其生活质量，本病例强调了姑息性手术在此类病例中的重要性。
