唾液β-葡萄糖醛酸酶活性作为牙周病标志物的评估：一项病例对照研究。
Estimation of salivary β-glucuronidase activity as a marker of periodontal disease: A case control study.
作者信息
Prabhahar Chandra Sekhara, Niazi K Thanvir Mohamed, Prakash R, Yuvaraj A, Goud Somasekhar, Ravishekar P
机构信息
Department of Periodontology, Best Dental Science College, Madurai, India.
Department of Oral and Maxillofacial Surgery, CSI College of Dental Sciences and Research, Madurai, India.
出版信息
J Int Soc Prev Community Dent. 2014 Dec;4(Suppl 3):S193-8. doi: 10.4103/2231-0762.149039.
AIM
The aim of the present study was to estimate the salivary β-glucuronidase level in healthy and diseased periodontium and to correlate the level with clinical measurement.
MATERIALS AND METHODS
70 patients were included in this study with the age ranging from 30 to 65 years. Both males and females were included. They were divided into two groups: Control having healthy periodontium (n = 20) and experimental having diseased periodontium (n = 50). The parameters recorded were probing pocket depth, probing attachment level, gingival index, β-glucuronidase activity in the saliva, number of white blood cells, neutrophils, lymphocytes count, and platelet count.
RESULTS
It was observed that there was an increase in the level of salivary β-glucuronidase in the experimental subjects than in the control patients, and a significant positive linear relationship existed between salivary β-glucuronidase level and probing pocket depth in the experimental group.
CONCLUSION
Level of salivary β-glucuronidase increases during inflammation in the periodontium.
目的
本研究旨在评估健康和患病牙周组织中唾液β-葡萄糖醛酸酶水平，并将该水平与临床测量结果相关联。
材料与方法
本研究纳入70例年龄在30至65岁之间的患者，男女均有。他们被分为两组：牙周健康的对照组（n = 20）和牙周患病的实验组（n = 50）。记录的参数包括探诊深度、探诊附着水平、牙龈指数、唾液中β-葡萄糖醛酸酶活性、白细胞数量、中性粒细胞、淋巴细胞计数和血小板计数。
结果
观察到实验组受试者唾液β-葡萄糖醛酸酶水平高于对照组患者，且实验组中唾液β-葡萄糖醛酸酶水平与探诊深度之间存在显著的正线性关系。
结论
牙周组织炎症期间唾液β-葡萄糖醛酸酶水平升高。
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