2012年，德国产毒素溃疡棒状杆菌的人畜共患病传播。
Zoonotic transmission of toxigenic Corynebacterium ulcerans strain, Germany, 2012.
作者信息
Meinel Dominik M, Konrad Regina, Berger Anja, König Christina, Schmidt-Wieland Torsten, Hogardt Michael, Bischoff Heribert, Ackermann Nikolaus, Hörmansdorfer Stefan, Krebs Stefan, Blum Helmut, Margos Gabriele, Sing Andreas
出版信息
Emerg Infect Dis. 2015 Feb;21(2):356-8. doi: 10.3201/eid2102.141160.
Abstract
Severe necrotizing fasciitis was diagnosed in a 53-year-old man in Germany in 2012. Toxigenic Corynebacterium ulcerans was grown from a wound swab sample. One of the patient's 2 dogs was found to harbor a toxigenic C. ulcerans strain. Results of next generation sequencing of both isolates supported recent zoonotic transmission of this bacterial pathogen.
摘要
2012年，德国一名53岁男子被诊断出患有严重坏死性筋膜炎。从伤口拭子样本中培养出产毒素的溃疡棒状杆菌。发现该患者的两只狗中有一只携带产毒素的溃疡棒状杆菌菌株。对这两种分离株进行的下一代测序结果支持了这种细菌病原体最近的人畜共患病传播。
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本文引用的文献
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Epidemiol Infect. 2014 Jul;142(7):1541-4. doi: 10.1017/S0950268813002240. Epub 2013 Sep 20.
2
Whole genome sequencing identifies zoonotic transmission of MRSA isolates with the novel mecA homologue mecC.全基因组测序鉴定出新型 mecA 同源物 mecC 的耐甲氧西林金黄色葡萄球菌分离株的人畜共患病传播。
EMBO Mol Med. 2013 Apr;5(4):509-15. doi: 10.1002/emmm.201202413. Epub 2013 Mar 25.
3
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