Rodríguez Argaiz F J, Rico Irles J, Gil Extremera B, Maldonado Martín A, Alvarez de Cienfuegos E
An Med Interna. 1989 Nov;6(11):571-4.
The brain's morphologic changes induced by chronic abuse of ethanol are studied, using the computerized tomography (CT) of 1005 clinical records reviewed during 1982-1987 at "Hospital Universitario de Granada", only 33 were selected as patients suffering from chronic alcoholism, CTs having been performed. The results were compared with 33 CTs of non-drinking patients. The ventricular index (VI), the evans' index (EI), the transversal diameter of third ventricle (TD) and cerebral sulcus evaluation were the values analysed to estimate the degree of cerebral atrophy. It was proven that a significant decrease of VI, an increase of EI, TD and cerebral sulcus in chronic alcoholic patients exists compared to non-drinkers. 70% of the alcoholic patients had cerebral atrophy. The conclusion of this study is that chronic alcoholism is an important causal factors of the cerebral atrophy process, regardless of age, alcohol intake quantity and/or the existence of other associate pathology.
利用1982年至1987年间在“格拉纳达大学医院”审查的1005份临床记录的计算机断层扫描（CT），研究了长期滥用乙醇引起的大脑形态学变化。仅33名被选为患有慢性酒精中毒且已进行CT检查的患者。将结果与33名非饮酒患者的CT结果进行比较。分析心室指数（VI）、埃文斯指数（EI）、第三脑室横径（TD）和脑沟评估值，以估计脑萎缩程度。结果证明，与非饮酒者相比，慢性酒精中毒患者的VI显著降低，EI、TD和脑沟增加。70%的酒精中毒患者有脑萎缩。本研究的结论是，慢性酒精中毒是脑萎缩过程的一个重要病因，与年龄、酒精摄入量和/或其他相关病理状况无关。
