Ozcımen Muammer, Sakarya Yasar, Goktas Sertan, Sakarya Rabia, Ivacık Ismail S, Yener Halil I, Erdogan Erkan
Department of Ophthalmology, Konya Training and Research Hospital, Konya, Turkey.
>Konya Eye Clinic, Konya, Turkey.
Arq Bras Oftalmol. 2014 Nov-Dec;77(6):368-72. doi: 10.5935/0004-2749.20140092.
This study was performed to evaluate the retinal nerve fiber layer (RNFL) and peripapillary choroidal thickness in eyes with tilted optic disc in order to identify characteristic RNFL and peripapillary choroid patterns verified by optical coherence tomography (OCT).
Twenty-nine eyes of 29 patients with tilted optic discs were studied with spectral-domain (SD)-OCT and compared with age and sex-matched control subjects in a prospective design. The imaging of RNFL was performed using circular scans of a diameter of 3.4 mm around the optic disc using OCT. For measurements of peripapillary choroidal thickness, the standard protocol for RNFL assessment was performed.
SD-OCT indicated significantly lower superotemporal (p<0.001), superonasal (p=0.001), and global (p=0.005) RNFL thicknesses in the tilted disc group than those of the control group. Peripapillary choroid was significantly thicker at the site of the elevated rim of eyes with tilted disc (p<0.001).
This study demonstrated a clinical characterization of the main tilted disc morphologies that may be helpful in differentiating a tilted disc from other altered disc morphologies. Further studies are recommended to study the comparison between glaucoma and tilted disc groups.
本研究旨在评估倾斜视盘眼的视网膜神经纤维层（RNFL）和视乳头周围脉络膜厚度，以确定经光学相干断层扫描（OCT）证实的特征性RNFL和视乳头周围脉络膜模式。
采用前瞻性设计，对29例倾斜视盘患者的29只眼进行了光谱域（SD）-OCT研究，并与年龄和性别匹配的对照受试者进行比较。使用OCT对视盘周围直径3.4 mm的圆形扫描进行RNFL成像。对于视乳头周围脉络膜厚度的测量，采用评估RNFL的标准方案。
SD-OCT显示，倾斜视盘组的颞上（p<0.001）、鼻上（p=0.001）和整体（p=0.005）RNFL厚度显著低于对照组。倾斜视盘眼的隆起边缘处视乳头周围脉络膜明显增厚（p<0.001）。
本研究展示了主要倾斜视盘形态的临床特征，这可能有助于将倾斜视盘与其他异常视盘形态区分开来。建议进一步研究青光眼组与倾斜视盘组之间的比较。
