Wiswell T E, Geschke D W
Medical Research Fellowship, Walter Reed Army Institute of Research, Washington, DC.
Pediatrics. 1989 Jun;83(6):1011-5.
The records of 136,086 boys born in US Army hospitals from 1980 to 1985 were reviewed for indexed complications related to circumcision status during the first month of life. For 100,157 circumcised boys, there were 193 complications (0.19%). These included 62 local infections, eight cases of bacteremia, 83 incidences of hemorrhage (31 requiring ligature and three requiring transfusion), 25 instances of surgical trauma, and 20 urinary tract infections. There were no deaths or reported losses of the glans or entire penis. By contrast, the complications in the 35,929 uncircumcised infants were all related to urinary tract infections. Of the 88 boys with such infections (0.24%), 32 had concomitant bacteremia, three had meningitis, two had renal failure, and two died. The frequencies of urinary tract infection (P less than .0001) and bacteremia (P less than .0002) were significantly higher in the uncircumcised boys. Serious complications from routine prepuce removal are rare and relatively minor. Circumcision may be beneficial in reducing the occurrence of urinary tract infections and their associated sequelae.
对1980年至1985年在美国陆军医院出生的136,086名男婴的记录进行了审查，以了解出生后第一个月内与包皮环切状况相关的索引并发症。在100,157名接受包皮环切术的男婴中，有193例并发症（0.19%）。这些并发症包括62例局部感染、8例菌血症、83例出血事件（31例需要结扎，3例需要输血）、25例手术创伤和20例尿路感染。没有死亡病例，也没有报告龟头或整个阴茎缺失的情况。相比之下，35,929名未接受包皮环切术的婴儿的并发症均与尿路感染有关。在88名患有此类感染的男婴中（0.24%），32例伴有菌血症，3例患有脑膜炎，2例患有肾衰竭，2例死亡。未接受包皮环切术的男婴尿路感染（P<0.0001）和菌血症（P<0.0002）的发生率显著更高。常规包皮环切术引起的严重并发症很少见且相对较轻。包皮环切术可能有助于减少尿路感染及其相关后遗症的发生。
