Effect of ipilimumab on the HIV reservoir in an HIV-infected individual with metastatic melanoma.
作者信息
Wightman Fiona, Solomon Ajantha, Kumar Sanjeev S, Urriola Nicolas, Gallagher Kerri, Hiener Bonnie, Palmer Sarah, Mcneil Catriona, Garsia Roger, Lewin Sharon R
机构信息
aDoherty Institute for Infection and Immunity, University of Melbourne bDepartment of Infectious Diseases, Alfred Hospital and Monash University cCentre for Biomedical Research, Burnet Institute, Melbourne, Victoria dDepartment of Medical Oncology eDepartment of Clinical Immunology, Royal Prince Alfred Hospital, Sydney fWestmead Millenium Institute, University of Sydney, Westmead, New South Wales, Australia.
出版信息
AIDS. 2015 Feb 20;29(4):504-6. doi: 10.1097/QAD.0000000000000562.
Abstract
摘要
相似文献
1
Effect of ipilimumab on the HIV reservoir in an HIV-infected individual with metastatic melanoma.伊匹单抗对一名患有转移性黑色素瘤的HIV感染者体内HIV储存库的影响。
AIDS. 2015 Feb 20;29(4):504-6. doi: 10.1097/QAD.0000000000000562.
2
Case Report: response to ipilimumab in a patient with HIV with metastatic melanoma.病例报告：一名合并转移性黑色素瘤的HIV患者对伊匹单抗的反应
J Clin Oncol. 2011 Nov 10;29(32):e792-4. doi: 10.1200/JCO.2011.36.9199. Epub 2011 Oct 11.
3
4
5
[Ipilimumab treatment of metastatic melanoma].[伊匹单抗治疗转移性黑色素瘤]
Ugeskr Laeger. 2015 Jan 26;177(2A):108-9.
6
Ipilimumab in melanoma with limited brain metastases treated with stereotactic radiosurgery.立体定向放疗治疗脑转移局限的黑色素瘤患者中使用伊匹单抗。
Melanoma Res. 2013 Jun;23(3):191-5. doi: 10.1097/CMR.0b013e32835f3d90.
7
Nivolumab success in untreated metastatic melanoma.纳武单抗治疗初治转移性黑色素瘤取得成功。
Lancet Oncol. 2015 Jan;16(1):e9. doi: 10.1016/S1470-2045(14)71129-5. Epub 2014 Nov 21.
8
Ipilimumab, a human monoclonal antibody for treatment of unresectable or metastatic melanoma.
Oncology (Williston Park). 2011 Jul;25(7 Suppl Nurse Ed):46-7.
9
Nursing management of patients with metastatic melanoma receiving ipilimumab.接受伊匹单抗治疗的转移性黑色素瘤患者的护理管理
Oncol Nurs Forum. 2013 May 1;40(3):215-8. doi: 10.1188/13.ONF.215-218.
10
Long-lasting responses under treatment with ipilimumab: an argument against maintenance therapy?接受伊匹单抗治疗后的持久反应：反对维持治疗的理由？
Dermatology. 2015;230(1):8-10. doi: 10.1159/000365078. Epub 2014 Dec 13.
引用本文的文献
1
Epigenetic drugs against human DNA viruses and retroviruses.针对人类DNA病毒和逆转录病毒的表观遗传药物。
Antiviral Res. 2025 Aug;240:106218. doi: 10.1016/j.antiviral.2025.106218. Epub 2025 Jun 23.
2
Latency Reversing Agents and the Road to an HIV Cure.潜伏期逆转剂与治愈艾滋病的道路。
Pathogens. 2025 Feb 27;14(3):232. doi: 10.3390/pathogens14030232.
3
Melanoma in people living with HIV: Immune landscape dynamics and the role of immuno- and antiviral therapies.HIV 感染者中的黑色素瘤：免疫景观动力学和免疫及抗病毒治疗的作用。
Cancer Metastasis Rev. 2024 Nov 29;44(1):9. doi: 10.1007/s10555-024-10230-6.
4
Immune checkpoint inhibitors in infectious disease.传染病中的免疫检查点抑制剂。
Immunol Rev. 2024 Nov;328(1):350-371. doi: 10.1111/imr.13388. Epub 2024 Sep 9.
5
HIV Persistence, Latency, and Cure Approaches: Where Are We Now?HIV 持续存在、潜伏期和治愈方法：我们现在在哪里？
Viruses. 2024 Jul 19;16(7):1163. doi: 10.3390/v16071163.
6
Making a Monkey out of Human Immunodeficiency Virus/Simian Immunodeficiency Virus Pathogenesis: Immune Cell Depletion Experiments as a Tool to Understand the Immune Correlates of Protection and Pathogenicity in HIV Infection.将人类免疫缺陷病毒/猴免疫缺陷病毒发病机制搞得一团糟：免疫细胞耗竭实验作为一种工具，用于理解 HIV 感染中的免疫保护相关性和致病性的免疫相关性。
Viruses. 2024 Jun 17;16(6):972. doi: 10.3390/v16060972.
7
Immune checkpoint inhibitors as potential therapy for reverting T-cell exhaustion and reverting HIV latency in people living with HIV.免疫检查点抑制剂作为逆转 T 细胞耗竭和逆转 HIV 潜伏的潜在治疗方法，用于 HIV 感染者。
Front Immunol. 2023 Dec 7;14:1270881. doi: 10.3389/fimmu.2023.1270881. eCollection 2023.
8
Immune Checkpoint Inhibitors and Infection: What Is the Interplay?免疫检查点抑制剂与感染：它们之间有什么相互作用？
In Vivo. 2023 Nov-Dec;37(6):2409-2420. doi: 10.21873/invivo.13346.
9
The efficacy and tolerability of latency-reversing agents in reactivating the HIV-1 reservoir in clinical studies: a systematic review.临床研究中潜伏逆转剂激活HIV-1储存库的疗效和耐受性：一项系统评价
J Virus Erad. 2023 Aug 19;9(3):100342. doi: 10.1016/j.jve.2023.100342. eCollection 2023 Sep.
10
New Concepts in Therapeutic Manipulation of HIV-1 Transcription and Latency: Latency Reversal versus Latency Prevention.治疗性操纵 HIV-1 转录和潜伏期的新概念：潜伏期逆转与潜伏期预防。
Viruses. 2023 Jul 31;15(8):1677. doi: 10.3390/v15081677.
本文引用的文献
1
Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial.泊马度胺，一种组蛋白去乙酰化酶抑制剂，用于抑制性抗逆转录病毒治疗的 HIV 感染患者潜伏病毒的再激活：一项 1/2 期、单组、临床试验。
Lancet HIV. 2014 Oct;1(1):e13-21. doi: 10.1016/S2352-3018(14)70014-1. Epub 2014 Sep 15.
2
Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy.在接受抑制性抗逆转录病毒治疗的HIV感染患者中，使用短期伏立诺他激活HIV转录。
PLoS Pathog. 2014 Nov 13;10(10):e1004473. doi: 10.1371/journal.ppat.1004473. eCollection 2014 Oct.
3
Immune monitoring of the circulation and the tumor microenvironment in patients with regionally advanced melanoma receiving neoadjuvant ipilimumab.接受新辅助伊匹单抗治疗的局部晚期黑色素瘤患者的循环和肿瘤微环境的免疫监测。
PLoS One. 2014 Feb 3;9(2):e87705. doi: 10.1371/journal.pone.0087705. eCollection 2014.
4
A pilot study assessing the safety and latency-reversing activity of disulfiram in HIV-1-infected adults on antiretroviral therapy.一项评估双硫仑对接受抗逆转录病毒治疗的HIV-1感染成人的安全性和逆转潜伏期活性的试点研究。
Clin Infect Dis. 2014 Mar;58(6):883-90. doi: 10.1093/cid/cit813. Epub 2013 Dec 12.
5
PD-1 coinhibitory signals: the link between pathogenesis and protection.PD-1 共抑制信号：发病机制与保护之间的联系。
Semin Immunol. 2013 Oct 31;25(3):219-27. doi: 10.1016/j.smim.2013.02.002. Epub 2013 Mar 31.
6
Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies.HIV-1 根除研究中病毒储存库测量方法的比较分析。
PLoS Pathog. 2013 Feb;9(2):e1003174. doi: 10.1371/journal.ppat.1003174. Epub 2013 Feb 14.
7
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy.伏立诺他治疗可打破抗逆转录病毒治疗患者的 HIV-1 潜伏。
Nature. 2012 Jul 25;487(7408):482-5. doi: 10.1038/nature11286.
8
HIV-specific TGF-beta-positive CD4+ T cells do not express regulatory surface markers and are regulated by CTLA-4.HIV特异性转化生长因子β阳性CD4 + T细胞不表达调节性表面标志物，且受细胞毒性T淋巴细胞相关抗原4调控。
AIDS Res Hum Retroviruses. 2010 Mar;26(3):329-37. doi: 10.1089/aid.2009.0149.
9
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.HIV储存库的大小和持久性由T细胞存活和稳态增殖驱动。
Nat Med. 2009 Aug;15(8):893-900. doi: 10.1038/nm.1972. Epub 2009 Jun 21.
10
Immune activation driven by CTLA-4 blockade augments viral replication at mucosal sites in simian immunodeficiency virus infection.在猴免疫缺陷病毒感染中，由CTLA-4阻断驱动的免疫激活增强了黏膜部位的病毒复制。
J Immunol. 2008 Apr 15;180(8):5439-47. doi: 10.4049/jimmunol.180.8.5439.
Zotero 插件