伊朗市场上四种广泛使用的牙膏中可利用氟化物和稳定氟化物的评估。
Assessment of available and stable fluoride in four widely-used toothpastes in the Iranian market.
作者信息
Yaghini Jaber, Kiani Sima, Mortazavi Shiva, Haghshenas Bahareh, Mogharehabed Ahmad
机构信息
Assistant Professor, Department of Periodontics, Torabinejad Research Center, Esfahan University of Medical Sciences, Isfahan, Iran.
Postgraduate Student, Department of Periodontology, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
J Dent (Tehran). 2014 Sep;11(5):604-9. Epub 2014 Sep 30.
OBJECTIVE
Presence of available and stable fluoride in a dentifrice formulation is a major requirement for an anti-caries effect. Although the available fluoride concentration in Iranian dentifrices has been reported in previous studies, there is little information on its stability; which is dependent upon dentifrice formulation. This study was done to assess the fluoride ion concentration and stability in four widely used dentifrices in Iran.
MATERIALS AND METHODS
In this analytical study, three samples of each brand of dentifrice (Nasim, Pooneh, Crest, and Signal) were purchased. Total fluoride (TF) and total soluble fluoride (TSF) concentrations were determined by ion specific electrodes. Data about TF were analyzed by one-way analysis of variance (ANOVA). Kruskal-Wallis and Mann-Whitney tests were used for nonparametric data (TSF).
RESULTS
All dentifrices had more than 1000 ppm of fluoride ions. TSF in Crest was significantly higher than in other dentifrices (P<0.0001) and was over the maximum permitted dose.
CONCLUSION
The TF concentration in Iranian toothpastes was sufficient to prevent caries.
目的
牙膏配方中存在可利用且稳定的氟化物是产生防龋效果的主要要求。尽管之前的研究报道了伊朗牙膏中可利用氟化物的浓度，但关于其稳定性的信息却很少；而稳定性取决于牙膏配方。本研究旨在评估伊朗四种广泛使用的牙膏中氟离子的浓度和稳定性。
材料与方法
在这项分析研究中，购买了每个品牌牙膏（纳西姆、普内、佳洁士和信号）的三个样品。通过离子特异性电极测定总氟（TF）和总可溶性氟（TSF）的浓度。关于TF的数据通过单因素方差分析（ANOVA）进行分析。对于非参数数据（TSF），使用了Kruskal-Wallis和Mann-Whitney检验。
结果
所有牙膏的氟离子含量均超过1000 ppm。佳洁士中的TSF显著高于其他牙膏（P<0.0001），且超过了最大允许剂量。
结论
伊朗牙膏中的TF浓度足以预防龋齿。
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