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运动员前交叉韧带重建术后补充氨基葡萄糖:一项随机安慰剂对照试验。

Glucosamine supplementation after anterior cruciate ligament reconstruction in athletes: a randomized placebo-controlled trial.

作者信息

Eraslan Ali, Ulkar Bulent

机构信息

a Department of Sports Medicine , Antalya Education and Research Hospital , Antalya , Turkey.

出版信息

Res Sports Med. 2015;23(1):14-26. doi: 10.1080/15438627.2014.975809.

DOI:10.1080/15438627.2014.975809
PMID:25630243
Abstract

Although glucosamine is commonly consumed by athletes, its effectiveness in sports injuries is still under debate. We aimed to investigate the effects of glucosamine to the rehabilitation outcomes of anterior cruciate ligament (ACL) reconstructed athletes. Glucosamine-sulfate (1000 mg daily, for 8 weeks) was administered to half of the cohort of 30 male athletes, the other half used a placebo. Both groups received the same rehabilitation protocol. Knee pain and functions were evaluated by a visual analogue scale (VAS), International Knee Documentation Committee (IKDC) and Lysholm scores before and after oral administration. Additionally, an isokinetic test was performed after the administration period. The scores revealed significant improvements in both groups after 8 weeks, but no significant difference was detected between groups in any of the parameters. Glucosamine supplementation did not improve the rehabilitation outcomes of athletes after ACL reconstruction. This is the first study investigating this topic. Further studies will help to obtain clear evidence about glucosamine efficacy on ACL injured or ACL reconstructed athletes.

摘要

尽管运动员经常服用葡萄糖胺,但其对运动损伤的有效性仍存在争议。我们旨在研究葡萄糖胺对前交叉韧带(ACL)重建运动员康复效果的影响。30名男性运动员被分成两组,一组每天服用硫酸葡萄糖胺(1000毫克,共8周),另一组服用安慰剂。两组接受相同的康复方案。在口服前后,通过视觉模拟量表(VAS)、国际膝关节文献委员会(IKDC)和Lysholm评分对膝关节疼痛和功能进行评估。此外,在给药期结束后进行了等速测试。评分显示两组在8周后均有显著改善,但在任何参数上两组之间均未检测到显著差异。补充葡萄糖胺并未改善ACL重建运动员的康复效果。这是第一项研究该主题的研究。进一步的研究将有助于获得关于葡萄糖胺对ACL损伤或ACL重建运动员疗效的明确证据。

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