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一种用于脉动血流作用下颈动脉的粘弹性流体-结构相互作用模型。

A viscoelastic fluid-structure interaction model for carotid arteries under pulsatile flow.

作者信息

Wang Zhongjie, Wood Nigel B, Xu Xiao Yun

机构信息

Department of Chemical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.

出版信息

Int J Numer Method Biomed Eng. 2015 May;31(5):e02709. doi: 10.1002/cnm.2709. Epub 2015 Feb 23.

DOI:10.1002/cnm.2709
PMID:25630788
Abstract

In this study, a fluid-structure interaction model (FSI) incorporating viscoelastic wall behaviour is developed and applied to an idealized model of the carotid artery under pulsatile flow. The shear and bulk moduli of the arterial wall are described by Prony series, where the parameters can be derived from in vivo measurements. The aim is to develop a fully coupled FSI model that can be applied to realistic arterial geometries with normal or pathological viscoelastic wall behaviour. Comparisons between the numerical and analytical solutions for wall displacements demonstrate that the coupled model is capable of predicting the viscoelastic behaviour of carotid arteries. Comparisons are also made between the solid only and FSI viscoelastic models, and the results suggest that the difference in radial displacement between the two models is negligible.

摘要

在本研究中,开发了一种包含粘弹性壁行为的流固耦合模型(FSI),并将其应用于脉动流作用下的理想化颈动脉模型。动脉壁的剪切模量和体积模量由Prony级数描述,其中参数可从体内测量中得出。目的是开发一种完全耦合的FSI模型,该模型可应用于具有正常或病理粘弹性壁行为的实际动脉几何形状。壁位移的数值解和解析解之间的比较表明,耦合模型能够预测颈动脉的粘弹性行为。还对仅固体模型和FSI粘弹性模型进行了比较,结果表明两个模型之间径向位移的差异可忽略不计。

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