Favaretto Niccolo', Fasanaro Elena, Staffieri Alberto, Marchese-Ragona Rosario, Staffieri Claudia, Giacomelli Luciano, Stramare Roberto, Ottaviano Giancarlo, Marioni Gino
Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy.
Department of Neurosciences, Otolaryngology Section, Treviso Branch, University of Padova, Treviso, Italy.
Am J Otolaryngol. 2015 Jul-Aug;36(4):559-64. doi: 10.1016/j.amjoto.2015.01.003. Epub 2015 Jan 8.
Before the widespread use of antibiotics, most deep neck infections (DNIs) stemmed from complicated pharyngeal infections. Nowadays, they seem to be due mainly to dental infections. In 2010, our group reported that DNIs originated from a major salivary gland in 14% of cases. The main endpoint of the present investigation was to review our experience of the diagnosis and treatment of DNIs of salivary gland origin. We also compared the characteristics of DNIs originating from salivary glands with those originating elsewhere.
Between 2000 and 2011, 44 patients were treated for DNIs of salivary origin at our institution. These patients were compared with 191 cases of DNI diagnosed as having other sites of origin.
RESULTS/CONCLUSIONS: In the present series, DNIs originating from a major salivary gland accounted for 19% of all cases of DNI of known origin. Patients with DNI of salivary gland origin were more likely to be elderly than those whose DNI originated from elsewhere (p=0.000). Our multivariate statistical model showed that comorbidities (p=0.051, statistical trend) and the need for surgical treatment (p=0.028) independently predicted long-term hospitalization for DNIs originating from a major salivary gland.
在抗生素广泛使用之前，大多数颈部深部感染（DNI）源于复杂的咽部感染。如今，它们似乎主要是由牙科感染引起的。2010年，我们团队报告称，14%的DNI病例起源于主要唾液腺。本研究的主要终点是回顾我们对唾液腺源性DNI的诊断和治疗经验。我们还比较了唾液腺源性DNI与其他部位源性DNI的特征。
2000年至2011年期间，我们机构对44例唾液源性DNI患者进行了治疗。将这些患者与191例诊断为其他起源部位的DNI病例进行比较。
结果/结论：在本系列中，起源于主要唾液腺的DNI占所有已知起源的DNI病例的19%。唾液腺源性DNI患者比其他部位源性DNI患者更有可能是老年人（p = 0.000）。我们的多变量统计模型显示，合并症（p = 0.051，有统计学趋势）和手术治疗需求（p = 0.028）独立预测了起源于主要唾液腺的DNI患者的长期住院情况。
