Dunne W Michael
bioMérieux, Inc., Durham, North Carolina, USA
J Clin Microbiol. 2015 Aug;53(8):2404-9. doi: 10.1128/JCM.03681-14. Epub 2015 Jan 28.
In order to maximize the benefit of prompt antimicrobial therapy and avoid the risk associated with inappropriate use of antimicrobial agents, patients with suspected sepsis must be rapidly differentiated from patients with systemic inflammatory response syndrome (SIRS). In combination with standard microbiological testing, a number of biomarkers have been recently evaluated for this purpose, and the performance characteristics of the most promising of these are reviewed.
为了使及时的抗菌治疗效益最大化,并避免与不恰当使用抗菌药物相关的风险,必须迅速将疑似脓毒症患者与全身性炎症反应综合征(SIRS)患者区分开来。结合标准微生物检测,最近已针对此目的对多种生物标志物进行了评估,并对其中最具前景的生物标志物的性能特征进行了综述。