Low Yin Yee Sharon, Lai Siang Hui, Ng Wai Hoe
Department of Neurosurgery, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433. sharon_yy_low@ nni.com.sg.
Singapore Med J. 2014 Nov;55(11):e187-90. doi: 10.11622/smedj.2014168.
Primary malignant B-cell-type dural lymphoma is a rare subtype of primary central nervous system lymphoma (PCNSL). We herein report an unusual case of diffuse B-cell lymphoma that presents as a chronic subdural haematoma without extracranial involvement. The notable aspects of this case include the patient's immunocompetence, a short clinical history of symptom onset, rapid neurological deterioration and a fi nal diagnosis of high-grade PCNSL. This case highlights the challenges neurosurgeons face, especially in the emergency setting, when the disease manifests in varied presentations.
原发性恶性B细胞型硬脑膜淋巴瘤是原发性中枢神经系统淋巴瘤（PCNSL）的一种罕见亚型。我们在此报告一例不寻常的弥漫性B细胞淋巴瘤病例，该病例表现为慢性硬膜下血肿，无颅外受累。该病例的显著特点包括患者免疫功能正常、症状发作的临床病史短、神经功能迅速恶化以及最终诊断为高级别PCNSL。该病例凸显了神经外科医生所面临的挑战，尤其是在急诊情况下，当疾病以多种表现形式出现时。
