双侧肾母细胞瘤的保肾手术
Nephron-sparing surgery for bilateral Wilms tumor.
作者信息
Kieran Kathleen, Davidoff Andrew M
机构信息
Division of Pediatric Urology, Department of Urology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, RCP 3238, Iowa City, IA, 52242-1089, USA,
出版信息
Pediatr Surg Int. 2015 Mar;31(3):229-36. doi: 10.1007/s00383-015-3668-1. Epub 2015 Jan 30.
Abstract
Synchronous bilateral disease occurs in approximately 5 % of children with Wilms tumor (WT), and is independently associated with an increased risk of renal insufficiency. Nephron-sparing surgery (NSS) allows preservation of renal mass and improved renal function. Published oncologic and functional outcomes with NSS to date are generally good, likely reflecting proper patient selection and excellent surgical technique during tumor excision, as well as appropriate use of upfront and adjuvant therapies. Here we highlight important issues regarding the use of NSS in children with bilateral Wilms tumor (BWT).
摘要
约5%的肾母细胞瘤（WT）患儿会出现双侧同步发病，且这与肾功能不全风险增加独立相关。保留肾单位手术（NSS）可保留肾脏组织并改善肾功能。迄今为止，已公布的NSS的肿瘤学和功能结果总体良好，这可能反映了恰当的患者选择、肿瘤切除过程中出色的手术技术，以及术前和辅助治疗的合理应用。在此，我们重点介绍双侧肾母细胞瘤（BWT）患儿使用NSS的重要问题。
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本文引用的文献
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Development of hypertension is less frequent after bilateral nephron sparing surgery for bilateral Wilms tumor in a long-term survey.在一项长期调查中，双侧保留肾单位手术治疗双侧 Wilms 肿瘤后高血压的发生频率较低。
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