Suppr超能文献

不建议进行常规门诊甲状腺手术。

Routine outpatient thyroid surgery cannot be recommended.

作者信息

Sørensen Kasper Reinholdt, Klug Tejs Ehlers

机构信息

Øre-næse-hals-afdeling H, Hoved-Neuro-Centret, Aarhus Universitetshospital, Bygn. 10, Nørrebrogade 44, 8000 Aarhus C, Denmark.

出版信息

Dan Med J. 2015 Feb;62(2).

Abstract

INTRODUCTION

More than 1,100 thyroid operations are performed annually in Denmark. The major concern regarding outpatient thyroid surgery (OTS) is post-thyroidectomy bleeding (PTB), which may cause compression of the trachea and compromise respiration. We aimed to explore the incidence of PTB and the exact timespan from surgery to PTB, and to identify risk factors for PTB in order to discuss whether OTS can be considered safe.

METHODS

Data from the Ear-Nose-Throat Department, Aarhus University Hospital, covering the period from January 2001 to August 2013 were collected from the THYRKIR database, and the medical records of patients with PTB were reviewed.

RESULTS

A total of 42 (2.8%) patients were re-operated due to PTB. Multivariate logistic regression analysis identified male gender (odds ratio (OR) = 1.85) and thyrotoxicosis (OR = 2.68) as risk factors for PTB. PTB occurred within 6 h of surgery in 63% of cases, between 6 and 24 h in 25% of cases, and more than 24 h after surgery in 13% of cases. One patient required urgent reoperation due to acute respiratory insufficiency.

CONCLUSION

Although a rare event, PTB is potentially life-threatening, and unselected routine OTS cannot be considered safe. Until more studies have been conducted on the selection of patients suitable for OTS, we recommend, as a minimum, that patients are observed for at least 6 h after surgery and subsequently stay at a nearby hospital hotel until discharge 16 to 24 h postoperatively.

FUNDING

not relevant.

TRIAL REGISTRATION

The study was approved by the Danish Data Protection Agency (1-16-02-170-14).

摘要

引言

丹麦每年进行超过1100例甲状腺手术。门诊甲状腺手术(OTS)的主要担忧是甲状腺切除术后出血(PTB),这可能导致气管受压并危及呼吸。我们旨在探讨PTB的发生率以及从手术到PTB的确切时间跨度,并确定PTB的风险因素,以便讨论OTS是否可被视为安全。

方法

从THYRKIR数据库收集了奥胡斯大学医院耳鼻喉科2001年1月至2013年8月期间的数据,并对PTB患者的病历进行了回顾。

结果

共有42例(2.8%)患者因PTB接受了再次手术。多因素逻辑回归分析确定男性(优势比(OR)=1.85)和甲状腺毒症(OR = 2.68)为PTB的风险因素。63%的病例PTB发生在手术后6小时内,25%的病例发生在6至24小时之间,13%的病例发生在手术后24小时以上。1例患者因急性呼吸功能不全需要紧急再次手术。

结论

尽管PTB是罕见事件,但有潜在生命危险,未经选择的常规OTS不能被视为安全。在对适合OTS的患者选择进行更多研究之前,我们建议至少在手术后观察患者6小时,随后让患者住在附近的医院酒店,直到术后16至24小时出院。

资金

无关。

试验注册

该研究经丹麦数据保护局批准(1-16-02-170-14)。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验