斑贴试验中对镍的阳性反应不能预测基于镍合金的房间隔缺损封堵器植入的临床结果。
Positive reactions to nickel on a patch test do not predict clinical outcome of nickel alloy-based atrial septal defect occluder implantation.
作者信息
Kim Hee Joo, Shin Jung U, Lee Jungsoo, Lee Hemin, Jin Shan, Kim Seo Hyeong, Noh Ji Yeon, Lee Kwang Hoon
机构信息
Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
出版信息
Dermatology. 2015;230(2):184-8. doi: 10.1159/000371511. Epub 2015 Jan 23.
BACKGROUND
Patch testing is thought to be necessary prior to metal device implantation to rule out metal allergy-related complications; however, there are controversies over the effects of nickel allergy on the outcome of nickel alloy-based device implantation.
OBJECTIVE
This study aimed to evaluate the adverse events in a Korean population of nickel allergy patients who underwent atrial septal defect (ASD) closure with a nickel-titanium alloy-based device.
METHODS
We retrospectively reviewed the medical records of patients who underwent ASD closure with a nitinol device.
RESULTS
Among 38 patients who had ASD closure, 4 of 5 nickel-allergic patients and 10 of the 33 non-nickel-allergic patients had post-closure complications. All patients fared well, without device failure culminating in device removal.
CONCLUSION
In this study, positive reactions to nickel in a patch test were not associated with adverse early or late outcomes following ASD closure with a nickel alloy-based device.
背景
人们认为在植入金属装置之前进行斑贴试验对于排除与金属过敏相关的并发症是必要的；然而，镍过敏对基于镍合金的装置植入结果的影响存在争议。
目的
本研究旨在评估在韩国人群中，使用镍钛合金装置进行房间隔缺损（ASD）封堵的镍过敏患者的不良事件。
方法
我们回顾性分析了接受镍钛诺装置封堵ASD的患者的病历。
结果
在38例接受ASD封堵的患者中，5例镍过敏患者中有4例以及33例非镍过敏患者中有10例出现封堵后并发症。所有患者情况良好，未出现导致装置移除的装置故障。
结论
在本研究中，斑贴试验对镍的阳性反应与使用镍合金装置封堵ASD后的早期或晚期不良结局无关。
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