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距骨颈骨折的治疗结果:一项系统评价与荟萃分析。

Outcomes of Talar Neck Fractures: A Systematic Review and Meta-analysis.

作者信息

Dodd Andrew, Lefaivre Kelly A

机构信息

Department of Orthopaedic Surgery, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

J Orthop Trauma. 2015 May;29(5):210-5. doi: 10.1097/BOT.0000000000000297.

Abstract

OBJECTIVES

To report the rates of osteonecrosis and subtalar arthritis after talar neck fractures and to examine if rates have changed over time.

DATA SOURCES

A systematic review and meta-analysis of the English literature was performed using EMBASE, MEDLINE, CENTRAL, and Cochrane in November 2011 and updated in November 2014.

STUDY SELECTION

Inclusion criteria were studies examining talar neck fractures that reported talar body osteonecrosis rates as a primary or secondary outcome. Exclusion criteria included case series with <10 patients or >50% pediatric patients, inability to isolate results of talar neck fractures, primary treatment of talar excision or arthrodesis, mean follow-up of <3 months, and non-English literature.

DATA EXTRACTION

Basic information was collected including journal, author, year published, level of evidence, number of fractures, and follow-up length. Specific information collected included fracture classifications, timing of interventions, method of treatment, osteonecrosis rates, subtalar arthrosis rates, and method of diagnosis of osteonecrosis.

DATA SYNTHESIS

Fixed-effects models were used for meta-analysis. The overall event rate of osteonecrosis was calculated and stratified based on Hawkins classification of the talar neck fractures. Mean rates of subtalar arthritis were calculated for all studies and for studies including >2 years of follow-up.

CONCLUSIONS

The overall rate of osteonecrosis was 0.312. Rates for Hawkins' types I-IV were 0.098, 0.274, 0.534, and 0.480, respectively. The mean rate of subtalar arthritis was 0.49 but increased to 0.81 in studies with >2 years of follow-up. Complication rates are high in talar neck fractures, and patients should be counseled accordingly.

摘要

目的

报告距骨颈骨折后骨坏死及距下关节炎的发生率,并探讨发生率是否随时间变化。

数据来源

2011年11月使用EMBASE、MEDLINE、CENTRAL和Cochrane对英文文献进行了系统评价和荟萃分析,并于2014年11月更新。

研究选择

纳入标准为研究距骨颈骨折并将距骨体骨坏死发生率作为主要或次要结局的研究。排除标准包括患者少于10例或儿科患者超过50%的病例系列、无法分离距骨颈骨折结果、距骨切除或关节融合术的初始治疗、平均随访时间少于3个月以及非英文文献。

数据提取

收集基本信息,包括期刊、作者、发表年份、证据水平、骨折数量和随访时长。收集的具体信息包括骨折分类、干预时机、治疗方法、骨坏死发生率、距下关节病发生率以及骨坏死的诊断方法。

数据合成

采用固定效应模型进行荟萃分析。计算骨坏死的总体发生率,并根据距骨颈骨折的Hawkins分类进行分层。计算所有研究以及随访时间超过2年的研究的距下关节炎平均发生率。

结论

骨坏死的总体发生率为0.312。Hawkins I-IV型的发生率分别为0.098、0.274、0.534和0.480。距下关节炎的平均发生率为0.49,但在随访时间超过2年的研究中升至0.81。距骨颈骨折的并发症发生率较高,应据此对患者进行咨询。

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