Ellis Jason A, Mejia Munne Juan C, Winfree Christopher J
Department of Neurological Surgery, Columbia University Medical Center, New York, New York.
J Neurosurg. 2015 Jul;123(1):283-8. doi: 10.3171/2014.12.JNS14645. Epub 2015 Jan 30.
OBJECT Trigeminal branch stimulation has been used in the treatment of craniofacial pain syndromes. The risks and benefits of such an approach have not been clearly delineated in large studies, however. The authors report their experience in treating craniofacial pain with trigeminal branch stimulation and share the lessons they have learned after 93 consecutive electrode placements. METHODS A retrospective review of all patients who underwent trigeminal branch electrode placement by the senior author (C.J.W.) for the treatment of craniofacial pain was performed. RESULTS Thirty-five patients underwent implantation of a total of 93 trial and permanent electrodes between 2006 and 2013. Fifteen patients who experienced improved pain control after trial stimulation underwent implantation of permanent stimulators and were followed for an average of 15 months. At last follow-up 73% of patients had improvement in pain control, whereas only 27% of patients had no pain improvement. No serious complications were seen during the course of this study. CONCLUSIONS Trigeminal branch stimulation is a safe and effective treatment for a subset of patients with intractable craniofacial pain.
目的 三叉神经分支刺激已用于治疗颅面部疼痛综合征。然而，在大型研究中，这种治疗方法的风险和益处尚未得到明确界定。作者报告了他们使用三叉神经分支刺激治疗颅面部疼痛的经验，并分享了他们在连续进行93次电极植入后所学到的经验教训。方法 对资深作者（C.J.W.）为治疗颅面部疼痛而进行三叉神经分支电极植入的所有患者进行回顾性研究。结果 2006年至2013年间，35例患者共植入了93个试验电极和永久电极。15例患者在试验刺激后疼痛控制得到改善，随后植入了永久刺激器，并平均随访了15个月。在最后一次随访时，73%的患者疼痛控制得到改善，而只有27%的患者疼痛没有改善。在本研究过程中未观察到严重并发症。结论 三叉神经分支刺激对于一部分顽固性颅面部疼痛患者是一种安全有效的治疗方法。
