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治疗青少年颞下颌关节紊乱:松弛训练和咬合矫正器治疗的随机、对照、序贯比较。

Treating temporomandibular disorders in adolescents: a randomized, controlled, sequential comparison of relaxation training and occlusal appliance therapy.

出版信息

J Oral Facial Pain Headache. 2015 Winter;29(1):41-50. doi: 10.11607/ofph.1285.

Abstract

AIMS

To compare the effects of occlusal appliance therapy (OA) and therapist-guided relaxation training (RT) on temporomandibular disorder (TMD) pain in adolescents, thereby replicating a previous randomized controlled trial, and to explore whether additional therapy administered in a crossover sequential design improves treatment outcomes.

METHODS

The study involved 64 adolescents, aged 12 to 19 years, experiencing TMD pain at least once a week and diagnosed with myofascial pain in accordance with the Research Diagnostic Criteria for TMD. For phase 1 of the study, subjects were randomly assigned to OA or RT; nonresponders were offered the other treatment in phase 2. Self-reports of TMD pain and clinical assessments were performed before and after treatment in each phase and 6 months after the last treatment phase. Differences in outcomes between treatment groups across the different phases were analyzed by analysis of covariance (ANCOVA), and for differences in proportions, the chi-square test was used.

RESULTS

After phase 1, a significantly higher proportion of adolescents treated with OA (62.1%) than those treated with RT (17.9%) responded to treatment, defined as a subjective report of "Completely well/Very much improved" or "Much improved." Similar differences in self- report of treatment effect occurred after phase 2. About two-thirds of all adolescents in both phases reported such an improvement level at the 6-month follow-up, including a somewhat higher proportion of phase 1 responders (79.2%) than phase 1 nonresponders (60%).

CONCLUSION

The findings suggest that, for adolescents with TMD pain, use of standardized clinical treatment with OA is more effective than RT on self-evaluation of treatment improvement. For nonresponders, subsequent crossover treatment might be useful to improve subjective TMD pain.

摘要

目的

比较咬合治疗(OA)和治疗师指导的放松训练(RT)对青少年颞下颌关节紊乱病(TMD)疼痛的疗效,以复制以前的随机对照试验,并探讨交叉序贯设计中附加治疗是否能改善治疗效果。

方法

该研究纳入了 64 名年龄在 12 至 19 岁之间、每周至少出现一次 TMD 疼痛且根据 TMD 研究诊断标准被诊断为肌筋膜疼痛的青少年。在研究的第一阶段,患者被随机分配到 OA 或 RT 组;在第二阶段,非应答者接受另一项治疗。在每一阶段治疗前后和最后一次治疗阶段后 6 个月,对 TMD 疼痛的自我报告和临床评估进行了评估。通过协方差分析(ANCOVA)对不同阶段治疗组之间的结果差异进行分析,对于比例差异,采用卡方检验。

结果

第一阶段后,接受 OA 治疗的青少年(62.1%)比接受 RT 治疗的青少年(17.9%)有更高的比例对治疗有反应,定义为自我报告“完全好转/非常好转”或“好转很多”。第二阶段后也出现了类似的治疗效果自我报告差异。在两个阶段的所有青少年中,约有三分之二报告了这种改善水平,包括第一阶段的应答者(79.2%)比第一阶段的无应答者(60%)略高。

结论

这些发现表明,对于 TMD 疼痛的青少年,使用 OA 进行标准化临床治疗比 RT 对自我评估的治疗改善更有效。对于无应答者,随后的交叉治疗可能有助于改善主观 TMD 疼痛。

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