J Oral Facial Pain Headache. 2015 Winter;29(1):91-6. doi: 10.11607/ofph.1340.
This article reports a case of masticatory muscle pain and progressive limited mouth opening secondary to amyotrophic lateral sclerosis (ALS), popularly known as Lou Gehrig's disease. The symptoms were first mistaken as those of temporomandibular disorders, before fatty degeneration of all masticatory muscles were discovered on magnetic resonance imaging (MRI). ALS should be considered in the differential diagnosis process when the patient presents with longstanding progressive mouth opening limitation associated with pain. MRI could facilitate the diagnostic process.
本文报告了一例因肌萎缩侧索硬化症（ALS），俗称葛雷克氏症，导致咀嚼肌疼痛和进行性张口受限的病例。最初症状被误诊为颞下颌关节紊乱，后来在磁共振成像（MRI）上发现所有咀嚼肌都发生了脂肪变性。当患者出现长期进行性张口受限伴疼痛时，应考虑 ALS 作为鉴别诊断。MRI 有助于诊断过程。
